Table 5.
Clinicopathological characteristics of RCC patients with and without CVs
| Variables | CV (+) n = 56 | CV (−) n = 67 | P-value |
|---|---|---|---|
| Sex (male); n (%) | 47 (83.9) | 53 (79.1) | 0.6432 |
| Age (years); median (IQR) | 67 (59–72) | 59 (49–68) | *0.0012 |
| BMI (kg/m2); median (IQR) | 23.5 (20.8–26.5) | 24.9 (21.3–27.2) | 0.1470 |
| ECOG PS (≥1); n (%) | 7 (12.5) | 0 (0) | *0.0033 |
| Charlson comorbidity index (≥1); n (%) | 22 (39.3) | 11 (16.4) | 0.3693 |
| Tumor size (mm); median (IQR) | 30 (25–35) | 23 (17–30) | * < 0.0001 |
| Tumor size > 2 cm | 51 (91.1) | 46 (68.7) | *0.0034 |
| Tumor location; n (%) | |||
| Right | 25 (44.6) | 29 (43.3) | 1.0000 |
| Posterior | 23 (41.1) | 26 (38.8) | 0.8543 |
| Lateral | 38 (67.9) | 38 (56.7) | 0.2639 |
| Exophytic; n (%) | 55 (98.2) | 61 (91.0) | 0.1248 |
| No round; n (%) | 43 (76.8) | 25 (37.3) | * < 0.0001 |
| Heterogeneity; n (%) | 50 (89.3) | 47 (70.1) | *0.0058 |
| CCC; n (%) | 52 (92.9) | 53 (79.1) | *0.0405 |
| Papillary RCC; n (%) | 3 (5.3) | 5 (7.5) | 0.7266 |
| Chromophobe RCC; n (%) | 1 (1.8) | 6 (9.0) | 0.1248 |
| Other types of RCC; n (%) | 0 (0.0) | 3 (4.4) | 0.2499 |
| pT3a; n (%) | 10 (17.8) | 4 (6.0) | *0.0482 |
| Fuhrman grade 3, 4; n (%) | 14 (25.0) | 11 (16.4) | 0.2669 |
| INFβ, γ; n (%) | 20 (35.7) | 13 (19.4) | 0.0650 |
| Central necrosis (+); n (%) | 12 (21.4) | 14 (20.9) | 1.0000 |
| MVI (+); n (%) | 31 (55.4) | 22 (32.8) | *0.0172 |
CV Collateral vessel, IQR Interquartile range, BMI Body mass index, ECOG PS Eastern Cooperative Oncology Group Performance Status, CCC Clear cell carcinoma, RCC Renal cell carcinoma, INF Infiltrative growth, MVI Microvascular invasion *p < 0.05