Table 3.
Assisted reproduction parameters and Embryo development outcomes in normal-weight (BMI > 24.5 kg/m2) and overweight (BMI ≤ 24.5 kg/m2) and whole studied population
| Parameters | normal weight (BMI < 24.5 kg/m2) (347) |
Overweight (BMI ≥ 24.5 kg/m2) (403) |
Whole studied population (750) |
P-Value |
|---|---|---|---|---|
| TEC |
8.9 ± 6.4 (2471) |
9.2 ± 7.0 (3942) |
9.1 ± 6.7 (6413) |
0.59 |
| MII |
7.7 ± 0.5 (2188) |
7.8 ± 0.6 (3292) |
7.7 ± 0.6 (5480) |
0.83 |
| 2PN |
5.3 ± 0.7 (1501) |
5.2 ± 0.2 (2091) |
5.2 ± 0.4 (3592) |
0.84 |
| FR | 74.8 ± 0.25 | 67 ± 0.2 | 70.2 ± 0.8 | 0.001 |
| D3 embryos | 3.8 ± 0.7 | 4.1 ± 0.4 | 4.0 ± 0.2 | 0.31 |
| EGA | 2.8 ± 0.9 | 2.7 ± 0.4 | 2.7 ± 0.6 | 0.89 |
| CR | 82.4 ± 0.24 | 83.5 ± 0.23 | 83.1 ± 0.24 | 0.56 |
| BR | 42.5 ± 0.24 | 39 ± 0.25 | 40.7 ± 0.24 | 0.42 |
| Aneuploidy (%) | 39.1 ± 2.1 | 38.1 ± 2.0 | 38.1 ± 1.4 | 0.45 |
| IR (%) | 131/347 (37%) | 143/403 (35%) | 274/750 (36%) | 0.51 |
| CLBR | 31.2 ± 3.4 | 20.1 ± 3.2 | 25.2 ± 3.4 | 0.02 |
| Birth weight (gm) | 2577.24 ± 30.94 | 2952.14 ± 53.64 | 2752.5 ± 36.98 | < 0.001 |
Values represent mean± SEM; BMI Body mass index, TEC Total egg collected, MII Metaphase two oocyte, 2PN Two pronuclei, FR Fertilization rate, D3 embryo Day three embryos, EGA, Embryo grade A, CR Cleavage rate, BR Blastocyst rate, IR Implantation rate, ET Number of embryo transferred, CLBR Cumulative live birth rate