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ADME analysis of the top three hits.
| Predicted ADME descriptors | ZINC000085569211 | ZINC000085569178 | ZINC000085569190 |
|---|---|---|---|
| QPlogPo/w (−2.0 to 6.5) | 3.141 | 3.781 | 5.148 |
| QPlogS (−6.5 to 0.5) | −3.535 | −4.845 | −5.611 |
| CIQPlogS (−6.5 to 0.5) | −6.078 | −6.915 | −8.312 |
| QPPCaco (<25 poor >500 great) | 19.986 | 18.883 | 19.63 |
| QPlogBB (−3.0to 1.2) | −2.047 | −2.353 | −2.594 |
| QPPMDCK (<25 poor >500 great) | 7.971 | 7.497 | 7.818 |
| HumanOralAbsorption (1, 2, or 3 for low, medium, or high) | 1 | 1 | 1 |
