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. 2022 Jul 22;16:900474. doi: 10.3389/fnins.2022.900474

TABLE 7.

Within-participant tests of difference over time for misophonic responses, psychosocial variables, and quality of life.

Measure Misophonia
General population
Baseline (n = 127)
Follow-up (n = 127)
Tests of within-participant difference over time
Baseline (n = 95)
Follow-up (n = 95)
Tests of within-participant difference over time
Item mean (SD) Lower CI, upper CI Item mean (SD) Lower CI, upper CI t(df) p Cohen’s d Item mean (SD) Lower CI, upper CI Item mean (SD) Lower CI, upper CI t (df) p Cohen’s d
MRS stand-alone items
Frequency 4.12
(1.19)
3.92,
4.31
3.90
(1.37)
3.66,
4.13
2.82
(126)
0.006 0.25 1.48
(0.80)
1.34,
1.64
1.62
(0.87)
1.48,
1.78
1.53
(94)
0.13 0.16
Recovery 4.00
(1.32)
3.76,
4.26
3.89
(1.31)
3.68,
4.11
1.19
(126)
0.24 0.11 2.27
(1.43)
2.00,
2.54
2.51
(1.40)
2.21,
2.77
1.51
(94)
0.13 0.16
Avoidance 5.65
(1.59)
5.37,
5.91
5.54
(1.66)
5.25,
5.82
0.96
(126)
0.34 0.09 2.22
(1.82)
1.87,
2.53
2.25
(1.70)
1.98,
2.56
0.16
(94)
0.88 0.02
MRS subscales
Emotional 5.72
(1.01)
5.54,
5.90
5.40
(1.26)
5.18,
5.60
3.95
(126)
<0.001 0.35 2.21
(1.24)
1.98,
2.44
2.36
(1.26)
2.10,
2.63
1.29
(94)
0.20 0.13
Physiological 3.19
(1.37)
2.96,
3.41
3.04
(1.47)
2.79,
3.31
1.83
(126)
0.070 0.16 1.54
(0.81)
1.39,
1.68
1.62
(0.82)
1.46,
1.77
1.08
(94)
0.28 0.11
Participation 4.15
(1.37)
3.91,
4.40
4.03
(1.44)
3.78,
4.28
1.30
(126)
0.20 0.12 1.56
(0.93)
1.39,
1.73
1.67
(1.11)
1.47,
1.88
0.97
(94)
0.34 0.10
MRS summed scores
Severity score 4.37
(0.98)
4.19,
4.54
4.17
(1.11)
3.97,
4.36
3.37
(126)
0.001 0.30 1.79
(0.91)
1.62,
1.98
1.90
(0.94)
1.73,
2.08
1.32
(94)
0.19 0.14
Weighted score 20.72
(7.65)
19.25,
22.17
19.24
(7.91)
17.68,
20.71
3.47
(126)
0.001 0.31 4.41
(4.80)
3.47,
5.30
4.87
(5.03)
4.02,
5.84
0.97
(94)
0.33 0.10
Psychosocial variables
Anger 2.38
(0.67)
2.26,
2.50
2.35
(0.67)
2.24,
2.47
0.58
(126)
0.56 0.05 1.73
(0.52)
1.63,
1.84
1.82
(0.54)
1.71,
1.94
1.97
(94)
0.05 0.20
Disgust 3.14
(0.69)
3.02,
3.27
3.06
(0.70)
2.94,
3.19
1.61
(126)
0.11 0.14 2.42
(0.54)
2.30,
2.54
2.43
(0.54)
2.31,
2.54
0.16
(94)
0.88 0.02
Anxiety 2.36
(0.68)
2.24,
2.47
2.26
(0.69)
2.14,
2.39
1.75
(126)
0.082 0.16 1.63
(0.60)
1.52,
1.74
1.80
(0.70)
1.67,
1.94
2.65
(94)
0.009 0.27
Self-esteem 2.78
(0.65)
2.66,
2.91
2.87
(0.67)
2.75,
3.00
2.53
(126)
0.013 0.22 3.30
(0.52)
3.20,
3.40
3.24
(0.54)
3.13,
3.35
2.03
(94)
0.045 0.21
Depression 2.32
(0.58)
2.22,
2.42
2.24
(0.62)
2.13,
2.36
1.82
(126)
0.071 0.16 1.68
(0.51)
1.57,
1.79
1.75
(0.56)
1.64,
1.85
1.97
(94)
0.052 0.20
SF-36*
Physical functioning 85.47
(19.93)
81.56,
88.79
84.88
(19.38)
81.26,
88.56
0.69
(126)
0.49 0.06 90.68
(12.15)
87.85,
93.05
89.58
(14.54)
86.40,
92.63
1.32
(94)
0.19 0.14
Role limitations – physical health 72.83
(39.34)
66.27,
78.88
76.18
(35.89)
69.98,
82.11
1.00
(126)
0.32 0.09 91.32
(24.67)
85.67,
95.88
85.00
(30.16)
78.91,
90.80
2.34
(94)
0.019 0.25
Role limitations – emotional problems 48.82
(43.20)
41.01,
55.71
52.49
(42.11)
45.32,
59.51
1.02
(126)
0.31 0.09 78.60
(35.37)
71.37,
85.54
72.98
(35.83)
65.73,
80.21
1.39
(94)
0.17 0.14
Energy/Fatigue 40.98
(20.87)
37.19,
44.62
42.01
(21.02)
37.94,
45.69
0.65
(126)
0.52 0.06 58.74
(20.63)
54.58,
62.32
54.79
(21.79)
50.28,
58.92
2.48
(94)
0.015 0.25
Emotional wellbeing 55.40
(19.85)
52.03,
58.86
57.42
(20.07)
53.65,
61.30
1.54
(126)
0.13 0.14 76.08
(16.59)
72.51,
80.04
72.25
(17.30)
68.95,
75.47
2.89
(94)
0.005 0.30
Social functioning 62.99
(27.57)
58.17,
67.74
67.72
(28.19)
62.73,
72.48
2.28
(126)
0.024 0.20 88.42
(19.57)
83.63,
92.42
84.61
(18.64)
80.31,
88.25
2.01
(94)
0.047 0.21
Pain 71.56
(22.95)
67.59,
75.51
72.52
(22.97)
68.49,
76.31
0.58
(126)
0.56 0.05 80.16
(17.44)
76.41,
83.97
77.58
(18.69)
73.48,
81.13
1.68
(94)
0.097 0.17
General health 62.20
(20.78)
58.53,
65.94
63.66
(19.86)
59.97,
67.29
1.20
(126)
0.23 0.11 68.11
(19.71)
64.09,
72.00
68.05
(22.31)
63.55,
72.69
0.04
(94)
0.97 0.004

*Total means reported for SF36 subscales.