TABLE 7.
Within-participant tests of difference over time for misophonic responses, psychosocial variables, and quality of life.
Measure | Misophonia |
General population |
||||||||||||
Baseline (n = 127) |
Follow-up (n = 127) |
Tests of within-participant difference over time |
Baseline (n = 95) |
Follow-up (n = 95) |
Tests of within-participant difference over time |
|||||||||
Item mean (SD) | Lower CI, upper CI | Item mean (SD) | Lower CI, upper CI | t(df) | p | Cohen’s d | Item mean (SD) | Lower CI, upper CI | Item mean (SD) | Lower CI, upper CI | t (df) | p | Cohen’s d | |
MRS stand-alone items | ||||||||||||||
Frequency | 4.12 (1.19) |
3.92, 4.31 |
3.90 (1.37) |
3.66, 4.13 |
2.82 (126) |
0.006 | 0.25 | 1.48 (0.80) |
1.34, 1.64 |
1.62 (0.87) |
1.48, 1.78 |
1.53 (94) |
0.13 | 0.16 |
Recovery | 4.00 (1.32) |
3.76, 4.26 |
3.89 (1.31) |
3.68, 4.11 |
1.19 (126) |
0.24 | 0.11 | 2.27 (1.43) |
2.00, 2.54 |
2.51 (1.40) |
2.21, 2.77 |
1.51 (94) |
0.13 | 0.16 |
Avoidance | 5.65 (1.59) |
5.37, 5.91 |
5.54 (1.66) |
5.25, 5.82 |
0.96 (126) |
0.34 | 0.09 | 2.22 (1.82) |
1.87, 2.53 |
2.25 (1.70) |
1.98, 2.56 |
0.16 (94) |
0.88 | 0.02 |
MRS subscales | ||||||||||||||
Emotional | 5.72 (1.01) |
5.54, 5.90 |
5.40 (1.26) |
5.18, 5.60 |
3.95 (126) |
<0.001 | 0.35 | 2.21 (1.24) |
1.98, 2.44 |
2.36 (1.26) |
2.10, 2.63 |
1.29 (94) |
0.20 | 0.13 |
Physiological | 3.19 (1.37) |
2.96, 3.41 |
3.04 (1.47) |
2.79, 3.31 |
1.83 (126) |
0.070 | 0.16 | 1.54 (0.81) |
1.39, 1.68 |
1.62 (0.82) |
1.46, 1.77 |
1.08 (94) |
0.28 | 0.11 |
Participation | 4.15 (1.37) |
3.91, 4.40 |
4.03 (1.44) |
3.78, 4.28 |
1.30 (126) |
0.20 | 0.12 | 1.56 (0.93) |
1.39, 1.73 |
1.67 (1.11) |
1.47, 1.88 |
0.97 (94) |
0.34 | 0.10 |
MRS summed scores | ||||||||||||||
Severity score | 4.37 (0.98) |
4.19, 4.54 |
4.17 (1.11) |
3.97, 4.36 |
3.37 (126) |
0.001 | 0.30 | 1.79 (0.91) |
1.62, 1.98 |
1.90 (0.94) |
1.73, 2.08 |
1.32 (94) |
0.19 | 0.14 |
Weighted score | 20.72 (7.65) |
19.25, 22.17 |
19.24 (7.91) |
17.68, 20.71 |
3.47 (126) |
0.001 | 0.31 | 4.41 (4.80) |
3.47, 5.30 |
4.87 (5.03) |
4.02, 5.84 |
0.97 (94) |
0.33 | 0.10 |
Psychosocial variables | ||||||||||||||
Anger | 2.38 (0.67) |
2.26, 2.50 |
2.35 (0.67) |
2.24, 2.47 |
0.58 (126) |
0.56 | 0.05 | 1.73 (0.52) |
1.63, 1.84 |
1.82 (0.54) |
1.71, 1.94 |
1.97 (94) |
0.05 | 0.20 |
Disgust | 3.14 (0.69) |
3.02, 3.27 |
3.06 (0.70) |
2.94, 3.19 |
1.61 (126) |
0.11 | 0.14 | 2.42 (0.54) |
2.30, 2.54 |
2.43 (0.54) |
2.31, 2.54 |
0.16 (94) |
0.88 | 0.02 |
Anxiety | 2.36 (0.68) |
2.24, 2.47 |
2.26 (0.69) |
2.14, 2.39 |
1.75 (126) |
0.082 | 0.16 | 1.63 (0.60) |
1.52, 1.74 |
1.80 (0.70) |
1.67, 1.94 |
2.65 (94) |
0.009 | 0.27 |
Self-esteem | 2.78 (0.65) |
2.66, 2.91 |
2.87 (0.67) |
2.75, 3.00 |
2.53 (126) |
0.013 | 0.22 | 3.30 (0.52) |
3.20, 3.40 |
3.24 (0.54) |
3.13, 3.35 |
2.03 (94) |
0.045 | 0.21 |
Depression | 2.32 (0.58) |
2.22, 2.42 |
2.24 (0.62) |
2.13, 2.36 |
1.82 (126) |
0.071 | 0.16 | 1.68 (0.51) |
1.57, 1.79 |
1.75 (0.56) |
1.64, 1.85 |
1.97 (94) |
0.052 | 0.20 |
SF-36* | ||||||||||||||
Physical functioning | 85.47 (19.93) |
81.56, 88.79 |
84.88 (19.38) |
81.26, 88.56 |
0.69 (126) |
0.49 | 0.06 | 90.68 (12.15) |
87.85, 93.05 |
89.58 (14.54) |
86.40, 92.63 |
1.32 (94) |
0.19 | 0.14 |
Role limitations – physical health | 72.83 (39.34) |
66.27, 78.88 |
76.18 (35.89) |
69.98, 82.11 |
1.00 (126) |
0.32 | 0.09 | 91.32 (24.67) |
85.67, 95.88 |
85.00 (30.16) |
78.91, 90.80 |
2.34 (94) |
0.019 | 0.25 |
Role limitations – emotional problems | 48.82 (43.20) |
41.01, 55.71 |
52.49 (42.11) |
45.32, 59.51 |
1.02 (126) |
0.31 | 0.09 | 78.60 (35.37) |
71.37, 85.54 |
72.98 (35.83) |
65.73, 80.21 |
1.39 (94) |
0.17 | 0.14 |
Energy/Fatigue | 40.98 (20.87) |
37.19, 44.62 |
42.01 (21.02) |
37.94, 45.69 |
0.65 (126) |
0.52 | 0.06 | 58.74 (20.63) |
54.58, 62.32 |
54.79 (21.79) |
50.28, 58.92 |
2.48 (94) |
0.015 | 0.25 |
Emotional wellbeing | 55.40 (19.85) |
52.03, 58.86 |
57.42 (20.07) |
53.65, 61.30 |
1.54 (126) |
0.13 | 0.14 | 76.08 (16.59) |
72.51, 80.04 |
72.25 (17.30) |
68.95, 75.47 |
2.89 (94) |
0.005 | 0.30 |
Social functioning | 62.99 (27.57) |
58.17, 67.74 |
67.72 (28.19) |
62.73, 72.48 |
2.28 (126) |
0.024 | 0.20 | 88.42 (19.57) |
83.63, 92.42 |
84.61 (18.64) |
80.31, 88.25 |
2.01 (94) |
0.047 | 0.21 |
Pain | 71.56 (22.95) |
67.59, 75.51 |
72.52 (22.97) |
68.49, 76.31 |
0.58 (126) |
0.56 | 0.05 | 80.16 (17.44) |
76.41, 83.97 |
77.58 (18.69) |
73.48, 81.13 |
1.68 (94) |
0.097 | 0.17 |
General health | 62.20 (20.78) |
58.53, 65.94 |
63.66 (19.86) |
59.97, 67.29 |
1.20 (126) |
0.23 | 0.11 | 68.11 (19.71) |
64.09, 72.00 |
68.05 (22.31) |
63.55, 72.69 |
0.04 (94) |
0.97 | 0.004 |
*Total means reported for SF36 subscales.