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. 2022 Aug 1;17(1):49. doi: 10.5334/gh.1134

Table 1.

Demographic variables and baseline comorbidities.


GLOBAL (n = 1,435) MEXICO (MX) (n = 262) CENTRAL AMERICA AND CARIBBEAN (CAC) (n = 428) SOUTH AMERICA (SAM) (n = 745) p-VALUE*

Demographic Variables

Age (years) 57.95
(SD 16.62)
55.56
(SD 15.41)
59.86
(SD 16.91)
57.69
(SD 16.77)
0.002
0.003
0.094
0.222

Male gender 64.46% (925) 58.40% (153) 70.33% (301) 63.22% (471) 0.004
0.001
0.014
0.166

Baseline Comorbidities

Overweight/obesity (BMI ≥ 25) 61.25% (879) 80.92% (212) 64.95% (278) 52.21% (389) 0.001
0.001
0.001
0.001

Overweight
(BMI 25–29)
35.75% (513) 38.55% (101) 43.93% (188) 30.07% (224) 0.001
0.165
0.001
0.012

Obesity(BMI ≥ 30) 25.51% (366) 42.37% (111) 21.03% (90) 22.15% (165) 0.001
0.001
0.654
0.001

HBP 45.37% (651) 36.26% (95) 60.28% (258) 40.00% (298) 0.001
0.001
0.001
0.286

DBT 26.83% (385) 34.35% (90) 33.64% (144) 20.27% (151) 0.001
0.849
0.001
0.001

Former tobacco use 14.15% (203) 6.87% (18) 19.63% (84) 13.56% (101) 0.001
0.001
0.006
0.004

Active tobacco use 8.43% (121) 13.74% (36) 7.94% (34) 6.85% (51) 0.002
0.014
0.485
0.001

Ischemic heart disease 6.76% (97) 4.96% (13) 9.58% (41) 5.77% (43) 0.019
0.028
0.015
0.623

COPD 6.62% (95) 2.67% (7) 2.10% (9) 10.60% (79) 0.001
0.630
0.001
0.001

Renal failure 4.32% (62) 1.91% (5) 2.80% (12) 6.04% (45) 0.003
0.462
0.013
0.008

Myocardiopathy 4.74% (68) 0.00% (0) 9.11% (39) 3.89% (29) 0.001
0.001
0.001
0.001

Valvular heart disease 1.74% (25) 2.29% (6) 2.57% (11) 1.07% (8) 0.128
N/A

HIV 0.42% (6) 0.38% (1) 0.00% (0) 0.67% (5) 0.229
N/A

Notes: * Each cell contains four p-values. The first p-value corresponds to chi-squared test (for categorical variables) or one-way ANOVA test (for numerical variables). Only a p ≤ 0.016 was considered statistically significance.

The second, third, and fourth p-values correspond to multiple comparisons between groups: Mx and CAC, CAC and SAm, and SAm and Mx, respectively. We used multiple chi-squared tests and ANOVA with Bonferroni correction.

HBP: high blood pressure; DBT: diabetes; COPD: chronic obstructive pulmonary disease; HIV: human immunodeficiency virus.