Table 4.
Relationship between the absolute number of Bregs and its subset in PBMCs and the clinicopathological parameters of IBCa patients.
| Variables | All cases | Bregs (×103) | P value | PD-1+ Bregs (×103) | P value |
|---|---|---|---|---|---|
| IBCa | 114 | ||||
| Grade | |||||
| G1 | 14 | 11.61±15.12 | 0.556 | 1.38±1.87 | 0.679 |
| G2 | 73 | 8.95±6.73 | 1.11±1.48 | ||
| G3 | 27 | 9.70±8.21 | 0.95±1.15 | ||
| LN metastasis | |||||
| NO | 60 | 10.03±9.94 | 0.446 | 1.19±1.77 | 0.512 |
| YES | 54 | 8.81±6.44 | 1.01±1.00 | ||
| TNM | |||||
| T1 | 37 | 9.87±10.32 | 0.702 | 1.36±1.84 | 0.443 |
| T2 | 46 | 9.84±8.35 | 0.97±1.31 | ||
| T3~T4 | 31 | 8.33±5.89 | 1.01±1.11 | ||
| ER | |||||
| Negative | 40 | 8.68±7.16 | 0.475 | 1.18±1.68 | 0.682 |
| Positive | 74 | 9.87±9.09 | 1.06±1.32 | ||
| PR | |||||
| Negative | 60 | 9.47±7.33 | 0.983 | 1.16±1.52 | 0.655 |
| Positive | 54 | 9.44±9.62 | 1.04±1.38 | ||
| HER-2 | |||||
| Negative | 74 | 9.05±7.23 | 0.708 | 1.07±1.32 | 0.846 |
| Positive | 40 | 9.67±9.08 | 1.12±1.53 | ||
| Age | |||||
| <49y | 46 | 9.41±7.04 | 0.962 | 1.20±1.80 | 0.547 |
| ≥49y | 68 | 9.95±10.47 | 1.08±1.18 | ||
| Tumor size | |||||
| <3cm | 62 | 9.40±8.69 | 0.944 | 1.19±1.54 | 0.500 |
| ≥3cm | 52 | 9.51±8.24 | 1.00±1.35 | ||
| Subtype | |||||
| Luminal A | 17 | 12.08±13.85 | 0.464 | 1.21±1.72 | 0.217 |
| Luminal B | 58 | 9.10±7.07 | 1.00±1.18 | ||
| HER2-positive | 20 | 7.78±6.51 | 0.75±0.92 | ||
| TNBC | 19 | 9.94±7.86 | 1.67±2.17 | ||