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. Author manuscript; available in PMC: 2023 Feb 3.
Published in final edited form as: Cancer Res. 2022 Aug 3;82(15):2678–2691. doi: 10.1158/0008-5472.CAN-22-0656

Table 1: Comparison of Prior RBE Calculations with the Present Study.

RBE was calculated using LD50 values from 30-day survival studies in mice after whole-body irradiation. Irradiation was performed with high energy radionuclide γ-ray sources or megavoltage X-ray sources and compared to orthovoltage X-rays. HVL: Half-Value Layer.

Reference High Energy
Radiation
Orthovoltage X-
rays
LD50/High
(Gy)
LD50/Low
(Gy)
R.B.E.
(LD50/High/LD50/Low)
Kohn & Kallman, 1956 1000 kVp X-rays, 3.3 mm Pb HVL 250 kVp, 1.6 mm Cu HVL 7.58 6.36 1.19
Upton et al., 1956 Cobalt-60 γ-rays 250 kVp, 0.55 mm Cu HVL 7.30 5.28 1.38
Storer et al., 1957 Radium γ-rays 250 kVp, 2.6 mm Cu HVL 6.71 5.01 1.34
Radium γ-rays 250 kVp, 2.6 mm Cu HVL 7.20 5.58 1.29
Paterson et al., 1957 4 MV X-Rays 300 kVp 7.47 5.61 1.33
Present Study Cesium-137 γ-rays 300 kVp, 1 mm Cu HVL 8.12 6.72 1.21
Cesium-137 γ-rays 300 kVp, 4 mm Cu HVL (Thoraeus) 8.12 7.42 1.09