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. 2022 Aug 4;5(12):e202201432. doi: 10.26508/lsa.202201432

Figure 1. SARS-CoV-2 replicates in human fetal intestinal epithelium and infects enterocytes.

Figure 1.

(A, B) Growth curves for SARS-CoV-2 replication in 2D fetal intestinal monolayer model and 3D enteroid model, respectively. Viral RNA was measured by RT-qPCR analysis of the E gene in the culture medium collected at different time points. (C) Immunofluorescent staining of SARS-CoV-2 infected monolayer 24 hours postinfection. SARS-CoV-2 (yellow) infects enterocytes (purple, stained for villin). Scale bars, 100 μm. Data information: In (A, B), data are presented as geometric mean ± SEM.