Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 22;15:975820. doi: 10.3389/fnmol.2022.975820

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Chen, Zhang, Ding, Wu, Wang and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Changes of synaptic transmission in nucleus accumbens (NAc) after chronic 3-MMC injection. (A) Representative sEPSCs traces recorded in NAC 24 h after the last injection of drugs. (B,C) No difference in the frequency and the amplitude of sEPSCs in NAc after chronic 3-MMC injection. (D) Representative sIPSCs traces recorded in NAC 24 h after the last injection of drugs. (E,F) The amplitude of sIPSCs was decreased after chronic 3-MMC injection without change of frequency of sIPSCs, post hoc test, *P < 0.05, ***P < 0.001 significant differences for 3-MMC vs saline and METH vs saline respectively. For slice electrophysiology: 25 neurons from three rats with saline injection, 32 neurons from three rats with METH injection and 27 neurons from three rats with 3-MMC injection. Data are presented as mean values ± SEM.