Table 3.
MRM parameters for the sweeteners in the present study by LC–MS/MS.
Compound | Precursorion (m/z) | Production (m/z) | Cone voltage (V) | Collision energy (eV) |
---|---|---|---|---|
ACS-K | 162 | 82a | −34 | −18 |
162 | 78 | −34 | −41 | |
CYC | 178 | 80a | −74 | −35 |
178 | 96 | −74 | −31 | |
SAC | 182 | 42a | −61 | −48 |
182 | 106 | −61 | −27 | |
ASP | 293 | 261a | −40 | −14 |
293 | 200 | −40 | −20 | |
SCL | 395 | 359a | −103 | −18 |
397 | 361 | −91 | −16 | |
NHDC | 611 | 303a | −130 | −50 |
611 | 125 | −130 | −70 | |
STV | 641.2 | 479a | −183 | −61 |
641.2 | 317 | −183 | −69 | |
GA | 821 | 113a | −124 | −80 |
821 | 351 | −124 | −63 | |
DUL | 181 | 108a | 55 | 32 |
181 | 136 | 55 | 22 | |
NEO | 379 | 172a | 63 | 35 |
379 | 319 | 63 | 27 |
ACS-K = acesulfame potassium; ASP = aspartame; CYC = cyclamate; DUL = dulcin; GA = glycyrrhizic acid; LC–MS/MS = liquid chromatography–tandem mass chromatography; MRM = multiple reaction monitoring; NEO = neotame; NHDC = neohesperidin dihydrochalcone; SAC = saccharin; SCL = sucralose; STV = stevioside.
Ion for quantification.