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. 2022 Jul 22;13:923194. doi: 10.3389/fimmu.2022.923194

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Copyright © 2022 Deng, Tan, Zhou, Bai, Cao, Zhong, Huang, Ou, Guo, Liu, Yin, Chen, Luo, Sun and Sheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of TME in primary HGSOCs, metastatic HGSOCs, and ECs. (A) Workflow of the samples collected and the data analysis strategy. (B) Cell populations identified. The UMAP projection of 55802 single cells from HG_P (n=5), HG_M (N=3), EC_P (n=2), HG_Nor (n=1) samples shows the 10 main clusters with annotation. Each dot corresponds to a single cell, colored according to cell type. (C) Canonical cell markers are used to identify the clusters. (D) Barplots of the cell type and cancer subtypes for all 11 tumors. (E) The cancer subtypes proportion for each pathological group.