Table 1.

Functional enrichment analysis based on the upregulated genes in HGSOCs Scissor⁺ cells versus All other cells (Scissor^- and Background cells).

Pathological subtype	Category	Description	Log10(q)	Genes
HGSOC	Reactome Gene Sets	Peptide chain elongation	-35.94	COL3A1, MT1E, MT2A, ZFP36, FOS, HBB, RPS17, NNMT, RPL13A, COL6A2, COL6A1, RPS9, JUN, RPL31, SLC25A6, RPL34, SAT1, RPS4X, ZFP36L1, RPS6, EEF2, RPS5, RPL11, RPL13, RPL23, CEBPB, RPL10A, RPS12, RPS20, RPL19, RPL10, RPS16, RPLP2, ID1, ACTB, RPL18, RPS14, RPS3, RPL7
HGSOC	Reactome Gene Sets	Signaling by Receptor Tyrosine Kinases	-8.00	COL3A1, COL1A1, FOS, JUNB, ID3, COL6A2, EGR1, FOSB, LAMA4, NR4A1, COL6A1, MYC, FN1, ID1, ACTB
HGSOC	Reactome Gene Sets	ECM proteoglycans	-6.99	DCN, COL3A1, COL1A1, C3, TIMP1, HBB, COL6A2, HP, HTRA1, LAMA4, COL6A1, FN1, FTL
HGSOC	Hallmark Gene Sets	HALLMARK_TNFA_SIGNALING_VIA NFKB	-21.61	DCN, MT1E, MT2A, ZFP36, FOS, JUNB, EGR1, DUSP1, FOSB, CYR61, NR4A1, PNRC1, MYC, IER2, JUN, KLF4, SAT1, NR4A2, IER3, CEBPB, KLF6, EIF1, UGP2
HGSOC	Hallmark Gene Sets	HALLMARK_EPITHELIAL_MESENCHYMAL TRANSITION	-15.12	MGP, GAS1, DCN, COL3A1, COL1A1, TIMP1, VIM, NNMT, COL6A2, CYR61, HTRA1, JUN, FN1, SAT1, IGFBP4
HGSOC	Hallmark Gene Sets	HALLMARK_P53_PATHWAY	-7.88	GNB2L1, FOS, JUN, KLF4, SAT1, ZFP36L1, IER3, RPS12, RPL18, ISCU