Table 2. Plasma lipid profile (mg %) of patients treated with the study drug.
*p<0.05
LDL-C: Low-density lipoprotein-cholesterol; HDL-C: High-density lipoprotein-cholesterol; TC: Total cholesterol.
| Parameter | Day 0 | Day 15 | Day 46 | Day 76 | Day 106 | P-value (between Day 15 to Day 106) |
| Cholesterol (mg %) | 293.42 ± 43.62 | 291.58 ± 45.06 | 251.84 ± 28.83* | 239.71 ± 22.54* | 228.42 ± 33.67* | 0.0001* |
| % decrease | -- | -- | 12.42 ± 12.66 | 25.36 ± 10.21 | 20.14 ± 15.64 | |
| Triglyceride | 269.47 ± 52.41 | 265 ± 46.19 | 198.16 ± 52.18* | 169.21 ± 57.72* | 122.10 ± 43.98* | 0.0001* |
| % decrease | -- | -- | 24.62 ± 16.08 | 33.57 ± 25.20 | 52.02 ± 20.04 | |
| LDL-C | 192.16 ± 48.01 | 190.95 ± 49.67 | 159.58 ± 27.69* | 129.58 ± 27.46* | 151.63 ± 34.59* | 0.0001* |
| % decrease | -- | -- | 12.59 ± 23.05 | 28.79 ± 20.84 | 15.48 ± 28.42 | |
| HDL-C | 47.37 ± 5.36 | 47.11 ± 4.81 | 52.63 ± 8.23* | 51.05 ± 11.25 | 53.95 ± 11.37* | 0.02* |
| % increase | -- | -- | 12.91 ± 21.69 | 9.82 ± 28.98 | 15.41 ± 26.85 | |
| TC: HDL-C ratio | 6.3 ± 1.36 | 6.25 ± 1.28 | 4.85 ± 0.72* | 4.39 ± 1.15* | 4.39 ± 1.02* | 0.0001* |
| LDL-C: HDL-C ratio | 4.15 ± 1.29 | 4.07 ± 1.33 | 3.07 ± 0.67* | 2.73 ± 1.12* | 2.96 ± 1.001* | 0.001* |