Table 5.
Anti-inflammatory effects of Acalypha alnifolia leaf extracts—egg albumin-induced paw edema in rats.
| Treatment | Paw volume (mm)/time (h) | % inhibition | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| 0 h | 1 h | 2 h | 3 h | 4 h | ||
| Control | 5.43 ± 0.23 | 6.38 ± 0.07 | 5.80 ± 0.07 | 5.58 ± 0.08 | 5.55 ± 0.36 | — |
| STD indomethacin | 3.63 ± 0.26 | 4.65 ± 0.59 | 4.13 ± 0.04 | 3.68 ± 0.80 | 3.68 ± 0.03* | 88.37 |
| AAAE (200 mg/kg) | 4.24 ± 0.39 | 5.64 ± 0.65 | 5.48 ± 0.47 | 5.34 ± 0.41 | 4.67 ± 0.08 | 27.90 |
| AAAE (400 mg/kg) | 4.13 ± 0.15 | 5.18 ± 0.15 | 5.3 ± 0.02 | 5.96 ± 0.21 | 4.44 ± 0.32* | 72.09 |
| AAME (200 mg/kg) | 4.29 ± 0.64 | 4.91 ± 0.68 | 4.93 ± 0.59 | 4.40 ± 0.64 | 4.67 ± 0.59 | 11.62 |
| AAME (400 mg/kg) | 4.31 ± 0.18 | 4.72 ± 0.17 | 5.3 ± 0.18 | 4.93 ± 0.19 | 4.45 ± 0.45* | 67.44 |
Data are expressed as the mean ± standard error of the mean.
*
p < 0.05.
AAAE = Acalypha alnifolia acetone extract; AAME = Acalypha alnifolia methanol extract; STD = standard.