Table 2.
Effect of oral administration of GABA and nattokinase on serum lipids.
| TG (mg/dL) | TC (mg/dL) | HDL (mg/dL) | LDL (mg/dL) | HDL/LDL (mg/dL) | UA (mg/dL) | |
|---|---|---|---|---|---|---|
| SHD | 64.5 ± 0.778b | 48.5 ± 0.707a | 24.0 ± 0.707b | 4.0 ± 0.414a | 6.0 | 2.1 ± 0.243bc |
| SMD | 59.0 ± 0.414b | 43.5 ± 0.707a | 22.5 ± 0.707bc | 4.5 ± 0.707a | 5.0 | 1.9 ± 0.141c |
| SLD | 61.5 ± 0.192b | 37.0 ± 0.828a | 22.5 ± 0.707bc | 4.0 ± 0.121a | 5.6 | 2.3 ± 0.424bc |
| SD | 62.5 ± 0.778b | 53.0 ± 0.556a | 21.0 ± 0.121c | 3.5 ± 0.707a | 6.0 | 3.6 ± 0.919a |
| SM | 59.0 ± 0.414b | 43.5 ± 0.607a | 21.0 ± 0.414c | 3.5 ± 0.707a | 6.0 | 2.0 ± 0.141bc |
| WHD | 102.5 ± 0.607a | 56.5 ± 0.364a | 33.5 ± 0.707a | 5.5 ± 0.707a | 6.1 | 2.2 ± 0.141bc |
| WD | 101.5 ± 0.707a | 58.0 ± 0.485a | 32.0 ± 0.414a | 5.5 ± 0.707a | 5.8 | 3.0 ± 0.283ab |
Different letters indicate a significant difference (p < 0.05, mean ± SD).
GABA = γ-aminobutyric acid; HDL = high-density lipoprotein; LDL = low-density lipoprotein; SD = negative control in the SHR; SHD = high dose of GABA and nattokinase in the SHR; SLD = low dose of GABA and nattokinase in the SHR; SM = medium dose of GABA and nattokinase in the SHR; SMD = medium dose of GABA and nattokinase in the SHR; TC = total cholesterol; TG = triacyglycerols; UA = uric acid; WD = negative control in the WKY; WHD = high dose of GABA and nattokinase in the WKY.