Table 2.

Average food intakes and weight gain of HPC rats administered citrus fruit juices.

Groupsa	Diet treatments	Food intake (g/rat/d)	Weight gain (%)
I	Normal control rats (basal)	9.8 ± 0.2a	7.6 ± 0.4a
II	HPC control rats (basal)	9.9 ± 0.1a	21.9 ± 1.2b
III	HPC control rats + simvastatin	9.8 ± 0.2a	5.6 ± 0.4c
IV	HPC control rats + 0.5 mL grapefruit	9.8 ± 0.1a	14.2 ± 0.9d
V	HPC control rats + 1.0 mL grapefruit	9.8 ± 0.1a	9.2 ± 0.6e
VI	HPC control rats + 2.0 mL grapefruit	9.9 ± 0.1a	15.7 ± 0.8d
VII	HPC control rats + 0.5 mL shaddock	9.9 ± 0.1a	12.9 ± 1.1d
VIII	HPC control rats + 1.0 mL shaddock	9.8 ± 0.2a	8.4 ± 0.6a
IX	HPC control rats + 2.0 mL shaddock	9.7 ± 0.1a	6.5 ± 0.7c

HPC = hypercholesterolemic positive control, HCD = high-cholesterol diet. Data with the same superscript number on the same column are not significantly (p < 0.05) different.

^aGroup I – normal control rats fed basal diet; Group II – rats fed a HCD (positive control); Group III – rats fed a HCD receiving simvastatin orally; Group IV – rats fed HCD administered 0.5 mL grapefruit juice; Group V – rats fed HCD administered 1.0 mL grapefruit juice; Group VI – rats fed HCD administered 2.0 mL grapefruit juice; Group VII – rats fed HCD administered 0.5 mL shaddock juice; Group VIII – rats fed HCD administered 1.0 mL shaddock juice; and Group IX – rats fed HCD administered 2.0 mL shaddock juice.