FIGURE 5.
H2S alleviated myocardial injury in aging rats. (A) Levels of plasma LDH in aging rats. (B) Levels of plasma CK in aging rats. (C) Levels of plasma CK-MB in aging rats. (D) Representative HE-stained myocardial sections in aging rats and quantitative data on inflammatory or death cells in microscopic field (%). (E) Representative Masson-stained myocardial sections in aging rats and quantitative data on myocardial fibrosis (%). (F) Representative images of M-mode by echocardiography indicated LVAW and LVPW in aging rats. (G) Values of LVAW’d in aging rats. (H) Values of LVPW’d in aging rats. (I) HW/BW ratios in aging rats. (J) Representative Western blots for P53 and P21 expressions in myocardial tissues of aging rats. GAPDH was used as the internal control. (K) Quantitative analysis for the P53 expression in the myocardial tissue of aging rats. (L) Quantitative analysis for the P21 expression in the myocardial tissue of aging rats. Results are means ± SEM. A p-value of <0.05 was considered significant. LDH: lactate dehydrogenase. CK: creatine kinase. CK-MB: creatine kinase isoenzyme-MB. HW/BW: heart weight/body weight ratios.