Skip to main content
. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Nat Synth. 2022 Apr 11;1(5):352–364. doi: 10.1038/s44160-022-00052-1

Fig. 6 |. Ring expansions that leverage carbonyl chemistry.

Fig. 6 |

a, General reaction mechanism for the Dowd–Beckwith rearrangement reaction52 (top) with application demonstrated in the synthesis of salvileucalin C54 (bottom). b, Representative example of a rhodium-catalysed cyclobutanone rearrangement55. Expanded rings are highlighted in red for clarity. AIBN, azobisisobutyronitrile; COD, 1,5-cyclooctadiene; dppp, 1,3-bis(diphenylphosphino) propane.