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. 2022 Jul 22;13:924173. doi: 10.3389/fphar.2022.924173

TABLE 4.

Multivariate logistic regression analysis of AKI in hospitalized patients.

Variable β Wald value OR and 95% CI p-value
Age −0.01 1.50 0.99 (0.99∼1.00) 0.22
Operation
 Operation 0.87 185.41 2.39 (2.11∼2.71) <0.001
 Contrast examination −0.137 2.74 0.88 (0.75∼1.02) 0.10
Laboratory Values
 Scr 0.01 90.65 1.02 (1.01∼1.04) <0.001
 Leukocyte count 0.02 33.04 1.02 (1.01∼1.03) <0.001
 Platelet count −0.01 34.93 0.99 (0.92∼1.00) <0.001
 Red blood cell count −0.14 20.62 0.87 (0.82∼0.92) <0.001
 Uric acid 0.01 154.39 1.02 (1.01∼1.03) <0.001
 Total bilirubin 0.01 123.19 1.01 (1.01∼1.04) <0.001
 β-2 microglobulin 0.06 128.03 1.06 (1.05∼1.08) <0.001
Comorbidity
 Hypertension 0.12 4.90 1.13 (1.01∼1.26) 0.03
 Diabetes −0.07 1.31 0.94 (0.84∼1.05) 0.25
 Cerebral apoplexy 0.45 66.66 1.56 (1.40∼1.74) <0.001
 Anemia −0.05 0.45 0.95 (0.83∼1.10) 0.50
 Coronary heart disease −0.05 0.69 0.95 (0.84∼1.07) 0.41
 Pneumonia 0.41 64.37 1.51 (1.36∼1.66) <0.001
 Shock 1.13 181.56 3.09 (2.62∼3.65) <0.001
 Sepsis 0.19 1.13 1.21 (0.85∼1.73) 0.29
 Skin tissue infection 0.12 0.21 1.13 (0.66∼1.88) 0.65
 Neoplastic diseases −0.12 3.67 0.89 (0.79∼1.01) 0.01
 Heart failure 0.46 34.48 1.58 (1.35∼1.84) <0.001
 Chronic kidney insufficiency −0.45 15.17 0.64 (0.50∼0.80) <0.001
 Hypokalemia 0.02 0.03 1.11 (0.82∼1.26) 0.86
 Hyponatremia 0.12 0.84 1.13 (0.87∼1.45) 0.36
 Liver injury 0.28 0.85 1.32 (0.72∼2.34) 0.03
 Chronic Obstructive Pulmonary Disease 0.21 2.39 1.24 (0.94∼1.62) 0.12
 Acidosis 0.90 47.45 2.47 (1.91∼3.19) <0.001
Combination therapy
 NSAIDs 0.22 15.50 1.25 (1.12∼1.40) <0.001
 ACEI 0.01 0.02 1.01 (0.84∼1.22) 0.89
 ARB 0.19 7.99 1.20 (1.06∼1.37) 0.01
 PPI 0.35 29.81 1.41 (1.25∼1.60) <0.001
 β-lactam drugs 0.72 170.55 2.06 (1.85∼2.29) <0.001