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. 2022 Jul 22;10:953916. doi: 10.3389/fbioe.2022.953916

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Copyright © 2022 Wang, Zhao, Gao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Osteocyte-Exos-mediated communication within the skeletal micro-environment. Osteocyte-Exos promoted osteoblast differentiation through miR-181b-5p, and inhibited osteoblast differentiation through miR-218 and miR-124-3p.