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. 2022 Jul 26;16(7):e0010638. doi: 10.1371/journal.pntd.0010638

Fig 10. The effect of CFA/I-CS21 ETEC infection on barrier integrity and cytokine induction in ileal enteroid responses.

Fig 10

TEER values of differentiated ileal enteroid monolayers (35I) were recorded prior to and after 4 hr infection (A). The change in TEER over time is expressed as TEER (percentage change) and data presented are pooled from six independent experiments. The asterisks above the dots indicate statistically significant differences determined using one-way ANOVA with Bonferroni’s multiple-comparison test, compared to the TEER of the uninfected enteroid monolayers (Blank). **, p<0.01; ***, p<0.001. IL-8 secretion (pg) was measured following 8 hr infection of enteroid monolayers (35I) by wildtype CVD30 and its derivative CF-deficient mutant strains, and data presented are from one independent experiment (B). Each dot represents data collected from an individual monolayer. Statistically significant differences were calculated using one-way ANOVA with Bonferroni’s multiple-comparison test.