TABLE 2.

Outcomes of receiver operating characteristic curves and Youden index for six candidate miRNAs and the panel.

	AUC	p-Value	95% CI	Associated criterion	Sensitivity (%)	Specificity (%)
miR-18a-5p	0.704	< 0.001	0.627–0.773	>1.05	75.64	64.63
miR-138-5p	0.771	< 0.001	0.698–0.834	≤0.85	64.10	84.15
miR-141-3p	0.743	< 0.001	0.668–0.808	≤1.03	92.31	53.66
miR-181b-5p	0.620	0.0073	0.540–0.696	>1	73.08	50.62
miR-200a-3p	0.701	< 0.001	0.623–0.771	≤0.91	62.82	68.29
miR-363-3p	0.646	< 0.001	0.567–0.720	≤0.9	56.41	69.51
four-miRNA panel	0.908	< 0.001	0.852–0.948	>0.52483	80.77	88.89

AUC, area under curve; CI, confidence interval.