TABLE 1.
Descriptive statistics including means and SDs for the NF1 and control group at the three assessment time points.
| 5 months |
10 months |
14 months |
||||||||||
| Control group |
NF1 |
Control group |
NF1 |
Control group |
NF1 |
|||||||
| n | Mean (SD) | n | Mean(SD) | n | Mean(SD) | n | Mean(SD) | n | Mean(SD) | n | Mean(SD) | |
| Age (days) | 26 | 179.19(14.05) | 15 | 194.73(17.85) | 27 | 321.93(16.70) | 23 | 327.0(17.11) | 23 | 447.61(18.42) | 27 | 449.74(23.41) |
| Male gender | 26 | 18 | 15 | 8 | 27 | 16 | 23 | 12 | 23 | 13 | 27 | 13 |
| Maternal education (n) (secondary/undergrad/postgrad) | 24 | 2/9/13 | 11 | 7/2/2 | 26 | 2/10/14 | 22 | 14/5/3 | 23 | 2/7/14 | 25 | 14/8/3 |
| Mullen Scale of Early Learning T scores | ||||||||||||
| Gross motor | 26 | 43.69(9.41) | 15 | 37.40(9.73) | 27 | 34.89(11.78) | 23 | 30.0(10.25) | 23 | 36.74(13.37) | 27 | 31.96(12.75) |
| Visual reception | 26 | 47.27(6.33) | 15 | 37.47(11.53) | 27 | 48.85(7.99) | 23 | 43.96(8.08) | 23 | 35.09(8.88) | 27 | 33.67(5.17) |
| Fine motor | 26 | 42.92(10.46) | 15 | 32.80(6.99) | 27 | 51.63(12.88) | 23 | 42.13(11.29) | 23 | 49.65(12.18) | 27 | 43.85(11.07) |
| Receptive language | 26 | 36.88(11.28) | 14 | 25.71(9.31) | 27 | 39.26(8.96) | 23 | 34.87(7.73) | 23 | 32.87(6.50) | 27 | 28.22(6.01) |
| Expressive language | 26 | 41.85(7.45) | 15 | 35.13(6.35) | 27 | 36.85(9.89) | 23 | 39.95(12.57) | 23 | 37.09(8.80) | 27 | 38.19(10.18) |
| Vineland Adaptive Behaviour Scale | ||||||||||||
| Communication | 22 | 94.95(10.91) | 14 | 95.71(18.26) | 21 | 92.86(12.76) | 23 | 86.13(14.91) | 19 | 96.11(10.49) | 24 | 91.04(10.08) |
| Daily living skills | 22 | 86.32(19.86) | 14 | 92.71(18.26) | 22 | 102.45(10.76) | 23 | 93.74(9.14) | 18 | 93.44(8.39) | 23 | 95.52(10.85) |
| Socialisation | 23 | 98.70(12.26) | 14 | 101.36(14.21) | 22 | 98.77(10.04) | 21 | 92.76(14.59) | 18 | 94.22(9.79) | 23 | 97.96(9.43) |
| Motor | 21 | 88.67(12.99) | 14 | 85.07(13.37) | 21 | 95.76(16.86) | 23 | 76.91(14.86) | 18 | 101.67(9.49) | 24 | 93.42(11.13) |
| Adaptive behaviour composite | 19 | 90.63(11.92) | 14 | 92.29(11.13) | 20 | 96.80(10.44) | 21 | 85.86(12.85) | 17 | 95.29(9.73) | 23 | 95.29(9.36) |
| MacArthur Communication Inventory | ||||||||||||
| Receptive vocabulary | 21 | 15.38(15.52) | 22 | 36.05(48.97) | 19a | 77.47(68.37) | 22a | 74.64(72.61) | ||||
| Expressive vocabulary | 21 | 0.33(0.97) | 22 | 1.18(1.99) | 19b | 10.53(13.09) | 23 | 7.96(10.52) | ||||
| Infant Behaviour Questionnaire | ||||||||||||
| Surgency | 17 | 4.16(0.82) | 10 | 4.42(0.77) | 22 | 4.80(0.46) | 21 | 4.83(0.72) | 19 | 5.18(0.60) | 25 | 4.96(0.59) |
| Negative affectivity | 21 | 3.17(0.72) | 14 | 2.96(0.68) | 21 | 3.50(0.66) | 21 | 3.73(1.08) | 18 | 3.43(0.66) | 26 | 3.7(1.00) |
| Regulation capacity | 19 | 5.09(0.51) | 13 | 5.08(0.67) | 20 | 4.76(0.47) | 22 | 4.80(0.89) | 19 | 4.80(0.67) | 26 | 4.79(0.76) |
| Sleep and Settle Questionnaire | ||||||||||||
| Sleep at night (Min) | 25 | 454.80(194.55) | 11 | 480.0(228.57) | 22 | 555.5(185.86) | 22 | 479.32(212.86) | 19 | 570.26(136.14) | 22 | 469.77(149.24) |
| Number of night wakes | 25 | 2.5 (1.45) | 12 | 2.62(1.85) | 22 | 1.32 (1.20) | 23 | 1.72(2.09) | 19 | 1.11(1.50) | 24 | 1.60(1.34) |
| Time taken to settle | 24 | 15.81(24.79) | 12 | 23.20(49.63) | 22 | 11.79(13.36) | 20 | 17.47(16.76) | 19 | 8.40(10.60) | 23 | 16.74(16.88) |
| Total confidence | 25 | 9.36(1.36) | 13 | 9.23(1.36) | 22 | 9.09(1.27) | 23 | 9.00(1.35) | 19 | 9.53(0.70) | 25 | 9.04(1.17) |
| AOSI total score | 18 | 10 (5.13) | 24 | 12.13(4.88) | ||||||||
| MACI | ||||||||||||
| Sensitive responsiveness | 22 | 4.50(0.96) | 19 | 3.68(1.16) | 16 | 4.75(1.18) | 19 | 4.21(1.08) | ||||
| Non-directiveness | 22 | 4.59(0.96) | 19 | 4.0(1.11) | 16 | 4.88(1.20) | 19 | 4.21(1.08) | ||||
| Infant attentiveness | 22 | 4.55(1.22) | 19 | 3.58(1.17) | 16 | 4.94(1.06) | 19 | 4.37(1.21) | ||||
| Mutuality | 22 | 4.36(0.95) | 19 | 3.37(0.83) | 16 | 4.63(0.96) | 19 | 4.05(1.31) | ||||
The number of participant data available for each measure is indicated.
aOne data-point each in NF1 and control group removed as >4 SD above mean.
bOne data-point in control group removed as >4 SD above mean.