TABLE 1.
Baseline patient characteristics and perioperative data a .
| Characteristic | Acetaminophen (n = 116) | Placebo (n = 119) |
|---|---|---|
| Patient characteristics | ||
| Female, n/total N (%) | 49/116 (42%) | 53/119 (45%) |
| Age (yr), mean (SD) | 49.6 (12.6) | 50.3 (12.8) |
| Weight (kg), mean (SD) | 63.7 (11.7) | 64.8 (9.4) |
| Height (m), mean (SD) | 1.6 (0.1) | 1.6 (0.1) |
| Body mass index (kg/m2), mean (SD) | 23.7 (3.1) | 24.0 (2.7) |
| Perioperative data, mean (SD) | ||
| Duration of surgery (min) | 136.0 (65.2) | 126.1 (59.2) |
| Mean heart rate (per min) | 76.3 (11.1) | 77.3 (10.1) |
| Mean systolic blood pressure (mmHg) | 126.1 (12.9) | 126.7 (12.6) |
| Mean diastolic blood pressure (mmHg) | 78.4 (8.8) | 79.8 (9.1) |
| ASA status, n/total N (%) | ||
| I | 25/116 (22%) | 40/119 (34%) |
| II | 91/116 (78%) | 79/119 (66%) |
| Type of surgery, n/total N (%) | ||
| Total knee or hip arthroplasty | 25/116 (22%) | 29/119 (24%) |
| Posterior internal fixation cervical/thoracic/lumbar vertebra | 23/116 (20%) | 18/119 (15%) |
| Long bone fracture | 18/116 (16%) | 20/119 (17%) |
| Others | 50/116 (43%) | 52/119 (44%) |
SD, standard deviation; ASA, american society of anaesthesiologists.
a
The two groups did not differ significantly on any of the characteristics shown.