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. 2022 Aug 1;17:3385–3400. doi: 10.2147/IJN.S372377

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© 2022 Ren et al.

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Characterization of Fe₃O₄@ZnO NCs and Fe₃O₄@ZnO-Bru NCs. (A and B) TEM images of Fe₃O₄@ZnO NCs (A) and Fe₃O₄@ZnO-Bru NCs (B). Scale bar: 50 nm. Insert: TEM image with a larger magnification, scale bar: 20 nm; (C) FTIR of Fe₃O₄@ZnO NCs and Fe₃O₄@ZnO-Bru NCs; (D) Magnetic hysteresis loops of Fe₃O₄@ZnO NCs and Fe₃O₄@ZnO-Bru NCs. The saturation of Fe₃O₄@ZnO-Bru slightly decrease compared with Fe₃O₄@ZnO but is still superparamagnetic, indicating that our drug delivery systems have the potential to be directed to a certain area by externally applied magnetism. Insert: The NCs solution was changed from stable to aggregated state under the magnetic field; (E) Zeta potential.