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. 2022 Jul 22;13:942569. doi: 10.3389/fendo.2022.942569

Table 1.

Univariate analysis of clinical characteristics and ultrasound features of lymph nodes in metastatic and benign groups.

Metastasis Benign P value
No. of LNs 351 302
No. of patients 307 269
Clinical Characteristics
Sex Male 90 (29.3%) 64 (23.8%) 0.135
Female 217 (70.7%) 205 (62.2%)
Age 39.86 ± 12.13 43.46 ± 13.01 0.003
Side Right 175 (49.9%) 130 (43.0%) 0.082
Left 176 (51.1%) 172 (57.0%)
Location Central 57 (16.2%) 56 (18.5%) 0.438
Lateral 294 (83.8%) 246 (81.5%)
Ultrasound Features
Long-axis diameter 13.08 ± 7.62 11.98 ± 6.62 0.096
>11.55 167 (47.6%) 121 (40.1%) 0.054
<11.55 184 (52.4%) 181 (59.9%)
Short-axis diameter 6.21 ± 3.24 5.40 ± 2.42 0.001
>6.25 135 (38.5%) 78 (25.8%) 0.001#
<6.25 216 (61.5%) 224 (74.2%)
L/S ≤2 197 (56.1%) 145 (48.0%) 0.039#
>2 154 (43.9%) 157 (52.0%)
Shape Irregular 7 (2.0%) 5 (1.7%) 0.748
Regular 344 (98.0%) 297 (98.3%)
Border Unsharp 4 (1.1%) 10 (3.3%) 0.063*
Sharp 347 (98.9%) 292 (96.7%)
Hilum Absent 258 (73.5%) 147 (48.7%) 0.000#
Present 93 (26.5%) 155 (51.3%)
Echogenicity Hyperechoic 111 (31.6%) 19 (6.3%) 0.000#
Isoechoic or hypoechoic 240 (68.4%) 283 (93.7%)
Calcifications Present 212 (60.4%) 65 (21.5%) 0.000#
Absent 139 (39.6%) 237 (78.5%)
Cystic change Present 53 (15.1%) 1 (0.3%) 0.000*#
Absent 298 (84.9%) 301 (99.7%)
Vascularity pattern Abnormal flow 154 (43.9%) 34 (11.3%) 0.000#
Hilar flow or absent flow 197 (56.1%) 268 (88.7%)

*Using Fisher’s exact tests, others using chi-square (X2),# enrolled into Multivariate Logistic Regression.