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. 2022 Jul-Sep;26(3):450–459. doi: 10.5935/1518-0557.20210094

Table 2.

Baseline and clinical characteristics of patients.

Characteristics Group 1 (1-3 oocytes) Group 2 (4-9 oocytes) Group 3 (10-15 oocytes) Group 4 (>15 oocytes)
Age (years) 34.23±5.37 36.73±4.80 <0.001 33.1±5.02 34.18±4.75 <0.001 31.5±4.25 32.04±4.43 0.003 30.67±4.40 30.48±4.12 0.319
Duration of infertility (years) 5.3±3.67 6.56±4.14 0.006 5.67±3.99 6.06±3.97 0.029 5.24±3.39 5.73±3.66 <0.001 5.15±3.22 5.04±3.14 0.447
Type of infertility (n;%)
Primary
Secondary
157 (67.7)
75 (32.3)
75 (63.0)
44 (37.0)
0.383 727 (67.0)
358 (33.0)
663 (67.2)
324 (32.8)
0.935 760 (69.7)
330 (30.3)
852 (72.6)
322 (27.4)
0.135 534 (70.2)
227 (29.8)
1306 (73.2)
477 (26.8)
0.112
Previous IVF attempts (n) 1.19±0.93 1.20±0.65 0.927 1.13±0.41 1.15±0.76 0.505 1.15±0.51 1.13±0.68 0.559 1.13±0.42 1.14±0.85 0.915
Indications for IVF (n;%)
Tubal factor
Male factor
Female factor
Ovulation disorder
Endometriosis
Unexplained infertility
Others
28 (12.1)
90 (39.0)
64 (27.7)
3 (1.3)
0 (0.0)
4 (1.7)
42 (18.2)
7 (5.9)
42 (35.3)
46 (38.7)
0 (0.0)
0 (0.0)
0 (0.0)
24 (20.2)
0.084** 153 (14.1)
514 (47.4)
203 (18.7)
8 (0.7)
6 (0.6)
9 (0.8)
191 (17.6)
126 (12.8)
426 (43.2)
211 (21.4)
6 (0.6)
4 (0.4)
6 (0.6)
206 (20.9)
0.228 184 (16.9)
588 (53.9)
90 (8.3)
8 (0.7)
5 (0.5)
9 (0.8)
206 (18.9)
173 (14.8)
634 (54.1)
82 (7.0)
21 (1.8)
3 (0.3)
6 (0.5)
252 (21.5)
0.085 97 (12.7)
453 (59.5)
41 (5.4)
11 (1.4)
4 (0.5)
4 (0.5)
151 (19.8)
241 (13.5)
1025 (57.5)
65 (3.6)
83 (4.7)
2 (0.1)
14 (0.8)
352 (19.8)
<0.001
Antral Follicle Count (n) 10.83±6.96 7.73±5.20 0.001 12.14±6.62 10.59±6.59 <0.001 17.18±8.00 15.66±8.18 0.001 19.66±8.17 21.78±9.74 <0.001
AMH (ng) 1.7 (1.1-2.9) 1.6 (1.0-2.5) 0.231* 2.3 (1.4-3.8) 2.4 (1.7-3.8) 0.02* 3.7 (2.5-5.2) 3.9 (2.6-5.8) 0.01* 4.8 (3.3-6.9) 6.3 (4.2-9.1) <0.001*
Days of ovarian stimulation (n) 10.2±1.48 10.33±1.63 0.466 10.15±1.35 10.06±1.22 0.082 10.2±1.26 10.07±1.16 0.010 10.25±1.08 10.29±1.19 0.440
Total gonadotropin dose (IU) 2749.13± 765.5 2973.89± 678.46 0.006 2742.03± 743.62 2809.55± 657.56 0.031 2500.46± 808.11 2538.39± 799.4 0.273 2227.7± 823.94 2105.87± 844.82 <0.001
On hCG trigger day
Estradiol level (pg/ml)
1796 1584 0.044* 2090 2000 0.217* 2873 2678 0.076* 3316 3956 <0.001*
  (1208-2782) (1194-2133)   (1431-3253) (1440-2960)   (1948-4068) (1901-4032)   (2301-6638) (2740-7787)  
Progesterone level (ng/ml) 0.7 0.8 0.608* 0.8 0.8 0.554* 0.9 0.9 0.014* 0.9 1.1 <0.001*
  (0.5-1.0) (0.5-1.0)   (0.6-1.1) (0.6-1.1)   (0.6-1.2) (0.7-1.3)   (0.7-1.2) (0.8-1.5)  
Endometrial thickness (mm) 10.83±1.5 10.41±1.06 0.003 10.78±1.35 10.35±1.03 <0.001 10.91±1.36 10.37±1.01 <0.001 10.93±1.31 10.33±0.98 <0.001
Oocytes retrieved (n) 2.44±0.72 2.52±0.64 0.254 6.61±1.71 6.87±1.64 <0.001 12.34±1.66 12.3±1.72 0.595 19.09±3.12 22.84±6.59 <0.001
Metaphase II oocytes (n) 1.93±0.78 2.26±0.67 <0.001 5.43±2.08 5.96±1.72 <0.001 10.36±2.47 10.4±2.35 0.739 15.22±3.66 19.18±5.85 <0.001
Fertilization Rate 0.79±0.25 0.82±0.26 0.316 0.71±0.23 0.73±0.21 0.050 0.70±0.20 0.71±0.18 0.504 0.70±0.18 0.73±0.16 0.012
Cleavage Rate 1.0 (1.0-1.0) 1.0 (1.0-1.0) 0.015 1.0 (0.8-1.0) 0.8 (0.7-1.0) <0.001 0.8 (0.7-1.0) 0.8 (0.6-0.9) 0.003* 0.8 (0.6-0.9) 0.8 (0.6-0.9) 0.429*
High-score embryos on Day 3 (n) 1 (0 - 1) 0 (0 - 1) 0.310* 1 (0 - 2) 1 (0 - 2) 0.660* 2 (0 - 4) 1 (0 - 2) <0.001* 3 (0 - 7) 2 (0 - 3) <0.001*
Average embryos transferred (n) 1.71±0.77 1.78±0.70 0.442 2.58±0.79 2.53±0.70 0.074 2.88±0.57 2.71±0.57 <0.001 2.97±0.45 2.84±0.49 <0.001
Embryos frozen (n) 1.25±0.77 1.77±0.73 <0.001 3.44±1.55 3.47±1.49 0.705 5.76±2.23 5.62±2.33 0.145 8.2±3.29 10.52±4.78 <0.001