Table 2.
Characteristics | Group 1 (1-3 oocytes) | Group 2 (4-9 oocytes) | Group 3 (10-15 oocytes) | Group 4 (>15 oocytes) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Age (years) | 34.23±5.37 | 36.73±4.80 | <0.001 | 33.1±5.02 | 34.18±4.75 | <0.001 | 31.5±4.25 | 32.04±4.43 | 0.003 | 30.67±4.40 | 30.48±4.12 | 0.319 |
Duration of infertility (years) | 5.3±3.67 | 6.56±4.14 | 0.006 | 5.67±3.99 | 6.06±3.97 | 0.029 | 5.24±3.39 | 5.73±3.66 | <0.001 | 5.15±3.22 | 5.04±3.14 | 0.447 |
Type of infertility (n;%) Primary Secondary |
157 (67.7) 75 (32.3) |
75 (63.0) 44 (37.0) |
0.383 | 727 (67.0) 358 (33.0) |
663 (67.2) 324 (32.8) |
0.935 | 760 (69.7) 330 (30.3) |
852 (72.6) 322 (27.4) |
0.135 | 534 (70.2) 227 (29.8) |
1306 (73.2) 477 (26.8) |
0.112 |
Previous IVF attempts (n) | 1.19±0.93 | 1.20±0.65 | 0.927 | 1.13±0.41 | 1.15±0.76 | 0.505 | 1.15±0.51 | 1.13±0.68 | 0.559 | 1.13±0.42 | 1.14±0.85 | 0.915 |
Indications for IVF (n;%) Tubal factor Male factor Female factor Ovulation disorder Endometriosis Unexplained infertility Others |
28 (12.1) 90 (39.0) 64 (27.7) 3 (1.3) 0 (0.0) 4 (1.7) 42 (18.2) |
7 (5.9) 42 (35.3) 46 (38.7) 0 (0.0) 0 (0.0) 0 (0.0) 24 (20.2) |
0.084** | 153 (14.1) 514 (47.4) 203 (18.7) 8 (0.7) 6 (0.6) 9 (0.8) 191 (17.6) |
126 (12.8) 426 (43.2) 211 (21.4) 6 (0.6) 4 (0.4) 6 (0.6) 206 (20.9) |
0.228 | 184 (16.9) 588 (53.9) 90 (8.3) 8 (0.7) 5 (0.5) 9 (0.8) 206 (18.9) |
173 (14.8) 634 (54.1) 82 (7.0) 21 (1.8) 3 (0.3) 6 (0.5) 252 (21.5) |
0.085 | 97 (12.7) 453 (59.5) 41 (5.4) 11 (1.4) 4 (0.5) 4 (0.5) 151 (19.8) |
241 (13.5) 1025 (57.5) 65 (3.6) 83 (4.7) 2 (0.1) 14 (0.8) 352 (19.8) |
<0.001 |
Antral Follicle Count (n) | 10.83±6.96 | 7.73±5.20 | 0.001 | 12.14±6.62 | 10.59±6.59 | <0.001 | 17.18±8.00 | 15.66±8.18 | 0.001 | 19.66±8.17 | 21.78±9.74 | <0.001 |
AMH (ng) | 1.7 (1.1-2.9) | 1.6 (1.0-2.5) | 0.231* | 2.3 (1.4-3.8) | 2.4 (1.7-3.8) | 0.02* | 3.7 (2.5-5.2) | 3.9 (2.6-5.8) | 0.01* | 4.8 (3.3-6.9) | 6.3 (4.2-9.1) | <0.001* |
Days of ovarian stimulation (n) | 10.2±1.48 | 10.33±1.63 | 0.466 | 10.15±1.35 | 10.06±1.22 | 0.082 | 10.2±1.26 | 10.07±1.16 | 0.010 | 10.25±1.08 | 10.29±1.19 | 0.440 |
Total gonadotropin dose (IU) | 2749.13± 765.5 | 2973.89± 678.46 | 0.006 | 2742.03± 743.62 | 2809.55± 657.56 | 0.031 | 2500.46± 808.11 | 2538.39± 799.4 | 0.273 | 2227.7± 823.94 | 2105.87± 844.82 | <0.001 |
Endometrial thickness (mm) | 10.83±1.5 | 10.41±1.06 | 0.003 | 10.78±1.35 | 10.35±1.03 | <0.001 | 10.91±1.36 | 10.37±1.01 | <0.001 | 10.93±1.31 | 10.33±0.98 | <0.001 |
Oocytes retrieved (n) | 2.44±0.72 | 2.52±0.64 | 0.254 | 6.61±1.71 | 6.87±1.64 | <0.001 | 12.34±1.66 | 12.3±1.72 | 0.595 | 19.09±3.12 | 22.84±6.59 | <0.001 |
Metaphase II oocytes (n) | 1.93±0.78 | 2.26±0.67 | <0.001 | 5.43±2.08 | 5.96±1.72 | <0.001 | 10.36±2.47 | 10.4±2.35 | 0.739 | 15.22±3.66 | 19.18±5.85 | <0.001 |
Fertilization Rate | 0.79±0.25 | 0.82±0.26 | 0.316 | 0.71±0.23 | 0.73±0.21 | 0.050 | 0.70±0.20 | 0.71±0.18 | 0.504 | 0.70±0.18 | 0.73±0.16 | 0.012 |
Cleavage Rate | 1.0 (1.0-1.0) | 1.0 (1.0-1.0) | 0.015 | 1.0 (0.8-1.0) | 0.8 (0.7-1.0) | <0.001 | 0.8 (0.7-1.0) | 0.8 (0.6-0.9) | 0.003* | 0.8 (0.6-0.9) | 0.8 (0.6-0.9) | 0.429* |
High-score embryos on Day 3 (n) | 1 (0 - 1) | 0 (0 - 1) | 0.310* | 1 (0 - 2) | 1 (0 - 2) | 0.660* | 2 (0 - 4) | 1 (0 - 2) | <0.001* | 3 (0 - 7) | 2 (0 - 3) | <0.001* |
Average embryos transferred (n) | 1.71±0.77 | 1.78±0.70 | 0.442 | 2.58±0.79 | 2.53±0.70 | 0.074 | 2.88±0.57 | 2.71±0.57 | <0.001 | 2.97±0.45 | 2.84±0.49 | <0.001 |
Embryos frozen (n) | 1.25±0.77 | 1.77±0.73 | <0.001 | 3.44±1.55 | 3.47±1.49 | 0.705 | 5.76±2.23 | 5.62±2.33 | 0.145 | 8.2±3.29 | 10.52±4.78 | <0.001 |