Table 3.
Comparison of IVF outcomes between freeze-all and fresh embryo transfer strategy.
| IVF outcomes | Group 1 (1-3 oocytes) | Group 2 (4-9 oocytes) | Group 3 (10-15 oocytes) | Group 4 (>15 oocytes) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fresh | Freeze-all | p | Fresh | Freeze-all | p | Fresh | Freeze-all | p | Fresh | Freeze-all | p | |
| Live birth rate 1st embryo transfer (ET) Singleton livebirth per women Twin livebirth per women Total live birth per women |
24 (10.3) 7 (3.0) 31 (13.4) |
12 (10.1) 4 (3.4) 16 (13.4) |
0.939 1.000* 0.983 |
146 (13.4) 45 (4.1) 191 (17.6) |
151 (15.3) 71 (7.2) 223 (22.6) |
0.232 0.003 0.004 |
166 (15.2) 62 (5.7) 229 (21.0) |
266 (22.7) 113 (9.6) 379 (32.3) |
<0.001 <0.001 <0.001 |
111 (14.5) 43 (5.6) 154 (20.2) |
411 (23.0) 236 (13.2) 648 (36.3) |
<0.001 <0.001 <0.001 |
| Pregnancy rate 1st ET | 37 (15.9) | 27 (22.7) | 0.122 | 260 (24.0) | 316 (32.0) | <0.001 | 310 (28.4) | 509 (43.4) | <0.001 | 215 (28.2) | 853 (47.8) | <0.001 |
| Clinical pregnancy rate 1st ET | 31 (13.4) | 17 (14.3) | 0.811 | 196 (18.0) | 233 (23.6) | <0.002 | 241 (22.1) | 388 (33.0%) | <0.001 | 160 (21.0) | 670 (37.6) | <0.001 |
| Implantation rate 1st ET | 0.09±0.24 | 0.1±0.26 | 0.612 | 0.09±0.21 | 0.14±0.27 | <0.001 | 0.11±0.22 | 0.19±0.29 | <0.001 | 0.1±0.21 | 0.22±0.3 | <0.001 |
| Miscarriage | 0 (0.0) | 1 (0.8) | 0.315* | 0 (0.0) | 7 (0.6) | 0.005* | 7 (0.4) | 15 (0.9) | 0.067 | 6 (0.4) | 29 (1.0) | 0.040 |
| Ectopic Pregnancy | 2 (0.8) | 0 (0.0) | 1.000* | 13 (1.0) | 8 (0.7) | 0.432 | 17 (1.0) | 20 (1.3) | 0.516 | 20 (1.4) | 30 (1.1) | 0.324 |
| Moderate or severe Ovarian Hyperstimulation Syndrome |
0 (0.0) | 0 (0.0) | 1 (0.07) | 0 (0.0) | 1.000* | 0 (0.0) | 0 (0.0) | 3 (0.2) | 0 (0.0) | 0.038* | ||
*
Fisher's exact test