Table 1.
Incidence of major HIV-negative individuals in 2019, and change of age-standardized incidence during the periods 1990–2010 and 2010–2019 for both sexes.
| Group | Drug-susceptible tuberculosis | Extensively drug-resistant tuberculosis | Multidrug-resistant tuberculosis without extensive drug resistance | Tuberculosis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of incident cases, 2019 | Annualized rate of change of age-standardized incidence | Number of incident cases, 2019 | Annualized rate of change of age-standardized incidence | Number of incident cases, 2019 | Annualized rate of change of age-standardized incidence | Number of incident cases, 2019 | Annualized rate of change of age-standardized incidence | |||||
| 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | |||||
| Global | 10,077,419 (8,738,073 to 11,455,752) |
−31.8 (−34.3 to −29.3) |
−13.8 (−17.3 to −11.0) |
31,016 (21,115 to 45,110) |
– | 7.5 (−23.0 to 51.3) |
563,014 (312,112 to 973,098) |
504.0 (156.8 to 1421.3) |
−11.1 (−46.6 to 47.6) |
10,671,449 (9,395,605 to 12,194,100) |
−28.4 (−30.7 to −26.0) |
−13.6 (−15.4 to −11.7) |
| High SDI | 982,370 (851,387 to 1,134,431) |
−42.2 (−45.3 to −39.0) |
−20.6 (−22.8 to −18.3) |
2,432 (1,609 to 3,875) |
– | 12.2 (−26.5 to 70.3) |
22,415 (13,717 to 38,727) |
14.2 (−36.6 to 108.7) |
−23.5 (−55.2 to 26.3) |
1,007,217 (870,478 to 1,161,202) |
−41.4 (−44.4 to −38.3) |
−20.6 (−22.5 to −18.6) |
| High–middle SDI | 4,024,958 (3,443,847 to 4,629,602) |
−31.8 (−36.0 to −28.1) |
−26.1 (−30.8 to −21.9) |
72,070 (48,408 to 102,383) |
– | −3.7 (−32.8 to 44.0) |
482,617 (288,844 to 773,317) |
512.3 (111.4 to 1803.0) |
−33.4 (−57.2 to 10.4) |
4,579,645 (3,989,516 to 5,271,730) |
−23.0 (−26.0 to −19.5) |
−26.6 (−28.8 to −24.6) |
| Middle SDI | 9,015,100 (7936886 to 10,194,207) |
−45.6 (−47.6 to −43.6) |
−13.5 (−16.9 to −10.5) |
23,778 (14,148 to 39,473) |
– | 16.1 (−29.7 to 85.9) |
432,597 (215,512 to 797,771) |
179.9 (3.9 to 857.5) |
−16.5 (−55.2 to 48.9) |
9471475 (8,369,573 to 10,711,366) |
−43.3 (−44.9 to −41.6) |
−13.6 (−15.5 to −11.6) |
| Low–middle SDI | 17,500,166 (14,921,311 to 20,233,346) |
−37.4 (−40.6 to −34.2) |
−18.1 (−23.3 to −14.3) |
3,135,2 (14,502 to 61,831) |
– | 39.6 (−32.3 to 161.7) |
1,024,299 (390,379 to 2,262,371) |
1421.6 (351.2 to 5,385.7) |
−2.2 (−59.5 to 102.4) |
18,555,817 (1,608,7711 to 21,293,251) |
−34.4 (−37.1 to −31.5) |
−17.3 (−19.5 to −14.9) |
| Low SDI | 20,228,727 (17,704,872 to 22,958,495) |
−31.8 (−34.6 to −29.2) |
−18.5 (−21.6 to −15.6) |
15,135 (6,721 to 32,291) |
– | 48.0 (−35.5 to 242.3) |
903,688 (498,968 to 1,630,859) |
1,388.7 (572.5 to 3,070.8) |
0.1 (−44.7 to 86.5) |
21,147,549 (18,738,135 to 24,087,649) |
−29.4 (−31.9 to −27.0) |
−17.8 (−19.9 to −15.7) |
| High–income | 732,692 (635,151 to 849795) |
−48.3 (−51.1 to −45.5) |
−20.9 (−23.2 to −18.4) |
1,573 (993 to 2,597) |
– | 22.5 (−18.9 to 90.6) |
12,511 (7,896 to 20,652) |
−2.5 (−40.9 to 62.2) |
−21.6 (−48.1 to 21.9) |
746,776 (646,686 to 865,802) |
−47.8 (−50.7 to −45.0) |
−20.8 (−23.0 to −18.5) |
| High–income North America | 230,533 (197,720 to 270,984) |
−57.1 (−60.4 to −53.9) |
−25.4 (−27.4 to −23.3) |
400 (186 to 829) |
– | 21.8 (−43.7 to 141.8) |
3,180 (1,479 to 6,589) |
−81.4 (−89.4 to −65.8) |
−22.0 (−64.0 to 54.7) |
234,113 (201,052 to 275,784) |
−57.8 (−61.1 to −54.7) |
−25.3 (−27.2 to −23.3) |
| Australasia | 590,651 (507,362 to 696,802) |
−38.5 (−42.9 to −33.6) |
−3.9 (−9.3 to 2.0) |
2,106 (933 to 4,242) |
– | 131.5 (−18.6 to 530.7) |
16,753 (7,424 to 33,746) |
115.2 (−32.8 to 678.0) |
48.1 (−47.9 to 303.6) |
609,510 (522,345 to 715,371) |
−37.7 (−41.9 to −32.6) |
−2.7 (−7.8 to 2.5) |
| High–income Asia Pacific | 1,607,829 (1,377,005 to 1,874,647) |
−54.3 (−58.4 to −49.5) |
−22.6 (−26.4 to −18.5) |
2,529 (659 to 8,084) |
– | 8.1 (−67.6 to 189.1) |
20,115 (5,246 to 64,285) |
14.6 (−68.5 to 367.9) |
−30.8 (−79.3 to 85.0) |
1,630,472 (1,401,086 to 1,901,303) |
−53.9 (−58.0 to −49.0) |
−22.7 (−26.2 to −18.8) |
| Western Europe | 685,048 (576,372 to 812,893) |
−39.0 (−41.8 to −35.9) |
−21.9 (−24.6 to −19.0) |
2,005 (1,344 to 2,953) |
– | 27.9 (−10.9 to 82.6) |
15,945 (10,689 to 23,494) |
77.4 (0.6 to 208.8) |
−18.2 (−43.0 to 16.8) |
702,998 (591,087 to 833,887) |
−38.0 (−40.9 to −34.8) |
−21.7 (−24.4 to −18.9) |
| Southern Latin America | 1,173,708 (1009774 to 1,368,438) |
−49.9 (−53.9 to −45.4) |
−1.3 (−7.9 to 5.0) |
2,021 (549 to 6,350) |
– | 30.9 (−56.1 to 240.9) |
16,075 (4,365 to 50,501) |
155.7 (−31.2 to 1,162.8) |
−16.2 (−71.9 to 118.2) |
1,191,803 (1,031,101 to 1,389,821) |
−49.2 (−53.1 to −44.8) |
−1.5 (−8.0 to 4.9) |
| Central Europe, Eastern Europe, and Central Asia | 3,649,114 (2,975,777 to 4,450,656) |
−20.0 (−28.3 to −11.2) |
−33.3 (−40.3 to −25.6) |
265,316 (181,799 to 371,193) |
– | 4.8 (−26.5 to 53.1) |
1,210,897 (829,736 to 1,694,144) |
2,801.0 (1,081.2 to 6,781.8) |
−34.9 (−54.3 to −4.9) |
5,125,328 (4,306,898 to 6,134,301) |
9.8 (2.7 to 18.6) |
−32.4 (−36.1 to −28.6) |
| Eastern Europe | 4,645,812 (3,592,545 to 5,909,367) |
−14.5 (−26.5 to −2.0) |
−37.1 (−46.4 to −26.6) |
413,474 (258,785 to 607,709) |
– | 7.6 (−31.5 to 72.0) |
1,887,081 (1,181,052 to 2,773,550) |
2,604.2 (897.2 to 7,216.9) |
−33.1 (−57.5 to 6.8) |
6,946,367 (5,743,355 to 8,474,562) |
21.2 (12.0 to 32.2) |
−34.4 (−38.7 to −29.8) |
| Central Europe | 1,367,729 (1,175,106 to 1,605,953) |
−32.4 (−37.0 to −27.1) |
−25.1 (−28.9 to −21.2) |
6,455 (3,499 to 11,420) |
– | 4.6 (−59.6 to 149.3) |
29,460 (15,972 to 52,105) |
210.3 (31.7 to 610.0) |
−35.0 (−75.0 to 54.9) |
1,403,644 (1,203,102 to 1,642,587) |
−30.8 (−35.5 to −25.5) |
−25.2 (−28.6 to −21.4) |
| Central Asia | 4,163,006 (3,466,650 to 4,972,969) |
−32.8 (−37.3 to −27.9) |
−24.8 (−33.6 to −16.0) |
250,154 (165,407 to 351,612) |
– | −3.9 (−35.0 to 37.8) |
1,141,704 (755,001 to 1,604,852) |
122,63.4 (4268.0 to 412,20.1) |
−40.3 (−59.6 to −14.4) |
5,554,864 (4,800,209 to 6,410,598) |
−6.6 (−12.4 to −0.2) |
−27.9 (−31.7 to −23.8) |
| Latin America and Caribbean | 2,687,923 (2,322,433 to 3,118,899) |
−46.7 (−49.4 to −43.8) |
−11.3 (−14.7 to −8.1) |
8,076 (4,696 to 13,653) |
– | 44.8 (−10.7 to 128.8) |
102,262 (59,464 to 172,901) |
419.2 (125.6 to 1,116.2) |
−6.0 (−42.0 to 48.6) |
2,798,261 (2,407,528 to 3,248,892) |
−44.9 (−47.6 to −42.0) |
−11.0 (−13.9 to −8.1) |
| Central Latin America | 1,741,175 (1,509,253 to 1,998,885) |
−41.5 (−44.9 to −37.9) |
−5.8 (−9.8 to −1.9) |
4,234 (1789 to 8,384) |
– | 60.4 (−24.3 to 219.9) |
53,607 (22,652 to 106,151) |
1,159.6 (374.6 to 3,577.9) |
4.2 (−50.9 to 107.8) |
1,799,015 (1,566,902 to 2,059,309) |
−39.9 (−43.1 to −36.2) |
−5.4 (−8.6 to −2.0) |
| Andean Latin America | 6,124,687 (5,259,831 to 7,168,303) |
−62.0 (−65.2 to −58.6) |
−25.1 (−29.9 to −20.2) |
33,607 (18,646 to 56,365) |
– | 8.4 (−36.5 to 83.4) |
425,536 (236,132 to 713,547) |
251.6 (30.7 to 1,168.5) |
−29.6 (−58.7 to 19.2) |
6,583,829 (5,668,696 to 7,628,324) |
−59.4 (−62.6 to −55.9) |
−25.3 (−28.8 to −21.3) |
| Caribbean | 3,237,851 (2,819,755 to 3,712,534) |
−28.7 (−32.6 to −24.8) |
0.7 (−4.5 to 6.2) |
1,424 (508 to 3,752) |
– | 121.6 (−14.8 to 547.9) |
18,025 (6,435 to 47,514) |
−37.0 (−79.6 to 98.2) |
44.0 (−44.7 to 320.9) |
3,257,300 (2,830,119 to 3,740,111) |
−28.7 (−32.6 to −24.7) |
0.9 (−4.4 to 6.5) |
| Tropical Latin America | 2,685,272 (2,268,547 to 3,154,004) |
−38.4 (−42.1 to −34.2) |
−9.8 (−16.3 to −4.2) |
6,753 (1,427 to 18,456) |
– | 96.5 (−51.6 to 390.4) |
85,506 (18,069 to 233,712) |
2,677.4 (528.3 to 20,956.4) |
27.6 (−68.5 to 218.6) |
2,777,531 (2,349,676 to 3,274,901) |
−37.0 (−40.7 to −32.8) |
−8.8 (−14.1 to −3.7) |
| Southeast Asia, East Asia, and Oceania | 7,740,765 (6,824,498 to 8,685,989) |
−48.5 (−50.2 to −46.7) |
−16.3 (−19.7 to −13.3) |
21,884 (10,815 to 45,334) |
– | 2.3 (−49.3 to 103.4) |
240,008 (118,604 to 497,212) |
36.0 (−50.8 to 383.8) |
−33.8 (−67.2 to 31.6) |
8,002,657 (7,112,167 to 8,932,688) |
−47.2 (−48.6 to −45.7) |
−16.9 (−19.0 to −14.7) |
| East Asia | 4,216,185 (3,632,791 to 4,791,289) |
−43.4 (−46.5 to −39.9) |
−29.9 (−36.1 to −25.9) |
16,480 (3,769 to 50,367) |
– | −18.1 (−78.1 to 120.8) |
180,740 (41,330 to 552,404) |
3.4 (−65.7 to 360.6) |
−47.0 (−85.8 to 42.9) |
4,413,405 (3,925,381 to 4,929,774) |
−41.9 (−44.0 to −39.5) |
−30.8 (−32.6 to −28.5) |
| Southeast Asia | 16,218,276 (14,403,770 to 18,060,079) |
−54.0 (−55.5 to −52.4) |
−10.1 (−12.7 to −7.4) |
34,506 (20,369 to 56,154) |
– | 35.8 (−25.4 to 149.6) |
378,431 (223,424 to 615,799) |
438.9 (116.3 to 1,491.7) |
−12.1 (−51.8 to 61.5) |
16,631,213 (14,840,698 to 18,503,116) |
−52.9 (−54.5 to −51.3) |
−10.1 (−12.3 to −7.6) |
| Oceania | 10,005,424 (8,931,039 to 11,114,474) |
−25.1 (−28.0 to −22.0) |
−11.0 (−16.0 to −6.5) |
32,189 (12,006 to 72,679) |
– | 310.9 (3.9 to 1,388.1) |
353,027 (131,635 to 797,369) |
1,953.4 (418.5 to 9,235.6) |
165.9 (−32.8 to 862.9) |
10,390,640 (9,346,294 to 1,1462,527) |
−24.2 (−27.2 to −21.1) |
−8.7 (−12.5 to −5.1) |
| North Africa and Middle East | 2,550,310 (2,204,205 to 2958695) |
−42.0 (−45.0 to −38.4) |
−21.3 (−24.3 to −18.4) |
2,680 (1,633 to 4,496) |
– | 17.1 (−29.6 to 93.0) |
75,937 (46,262 to 127,391) |
884.2 (402.7 to 1,845.2) |
−22.9 (−53.6 to 27.2) |
2,628,927 (2,270,964 to 3,049,615) |
−40.3 (−43.4 to −36.7) |
−21.3 (−23.9 to −18.8) |
| South Asia | 20,480,991 (17,185,849 to 24013953) |
−37.4 (−41.6 to −33.2) |
−19.9 (−26.1 to −15.1) |
36,443 (10,237 to 83,179) |
– | 47.7 (−48.3 to 230.1) |
1,486,893 (417,644 to 3,393,773) |
4,155.7 (929.3 to 21,758.0) |
−2.3 (−65.8 to 118.2) |
22,004,327 (1,899,5837 to 25,346,862) |
−33.7 (−37.3 to −29.9) |
−18.8 (−21.2 to −16.2) |
| Sub–Saharan Africa | 23,240,221 (20,576,148 to 26,367,753) |
−23.4 (−26.1 to −20.7) |
−16.5 (−19.2 to −13.9) |
4,902 (3,291 to 7,452) |
– | 44.1 (2.6 to 113.5) |
759,768 (510,186 to 1,154,992) |
1,047.3 (557.4 to 1,920.5) |
−4.1 (−31.7 to 42.0) |
24,004,890 (2,125,7144 to 27,278,756) |
−21.4 (−24.1 to −18.6) |
−16.2 (−18.6 to −13.7) |
| Southern Sub–Saharan Africa | 33,196,173 (28600662 to 38,515,379) |
−19.3 (−24.7 to −12.3) |
−1.3 (−8.5 to 5.1) |
7,443 (3,754 to 14,316) |
– | 42.2 (−38.3 to 229.7) |
1,153,614 (581,862 to 2,219,107) |
662.7 (148.0 to 3,180.6) |
−5.4 (−59.0 to 119.2) |
34,357,230 (2,961,9366 to 39,715,574) |
−16.6 (−22.0 to −9.5) |
−1.5 (−7.9 to 3.9) |
| Western Sub–Saharan Africa | 17,327,843 (15,123,163 to 19,818,589) |
−24.0 (−28.3 to −19.9) |
−20.7 (−24.5 to −17.2) |
3,840 (1,786 to 7,886) |
– | 16.5 (−41.2 to 137.7) |
595,242 (276,819 to 1,222,360) |
1,001.2 (424.1 to 2,245.5) |
−22.5 (−60.9 to 58.1) |
17,926,925 (15,745,074 to 20,465,886) |
−21.5 (−25.9 to −17.4) |
−20.8 (−23.6 to −17.7) |
| Eastern Sub–Saharan Africa | 27,122,987 (23,891,709 to 30,941,243) |
−26.8 (−29.8 to −23.3) |
−16.0 (−19.1 to −13.0) |
5,918 (3,717 to 10,058) |
– | 75.0 (12.1 to 185.2) |
917,287 (576,147 to 1,558,791) |
2,275.7 (861.1 to 5,530.1) |
16.4 (−25.4 to 89.7) |
28,046,191 (24,753,966 to 32,002,059) |
−25.1 (−28.2 to −21.5) |
−15.2 (−18.1 to −12.5) |
| Central Sub–Saharan Africa | 29,618,907 (26,124,997 to 33,250,345) |
−1.8 (−6.9 to 2.3) |
−13.9 (−18.8 to −8.7) |
4,762 (1,263 to 13,700) |
– | 65.5 (−44.0 to 376.1) |
738,193 (195,674 to 2,122,783) |
603.6 (31.8 to 3,379.0) |
10.1 (−62.7 to 216.9) |
30,361,862 (27,020,825 to 33,866,880) |
−0.2 (−4.3 to 3.8) |
−13.4 (−17.8 to −8.9) |