Table 2.
The DALYs of major HIV–negative individuals in 2019, and change of age–standardized DALYs during the periods 1990–2010 and 2010–2019 for both sexes.
| Group | Drug–susceptible tuberculosis | Extensively drug–resistant tuberculosis | Multidrug–resistant tuberculosis without extensive drug resistance | Tuberculosis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of DALYs, 2019 | Annualized rate of change of age–standardized DALYs | Number of DALYs, 2019 | Annualized rate of change of age–standardized DALYs | Number of DALYs, 2019 | Annualized rate of change of age–standardized DALYs | Number of DALYs, 2019 | Annualized rate of change of age–standardized DALYs | ||||||
| 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | ||||||
| Global | 53,422,865 (46,676,267 to 59,669,580) |
−51.6 (−55.9 to −47.3) |
−29.8 (−35.9 to −23.3) |
381,509 (189,136 to 668,316) |
— | −8.2 (−33.7 to 31.8) |
5,238,076 (2,263,595 to 9,759,929) |
386.5 (137.5 to 1006.8) |
−22.7 (−51.5 to 21.3) |
59,042,451 (53,684,783 to 64,641,528) |
−47.5 (−50.6 to −43.4) |
−29.1 (−34.5 to −23.6) |
|
| High SDI | 1,864,033 (1,657,623 to 2,112,640) |
−69.1 (−71.6 to −66.5) |
−28.2 (−33.7 to −21.4) |
17,269 (8,183 to 33,055) |
— | −7.5 (−35.2 to 30.2) |
83,813 (37,325 to 173,545) |
−28.2 (−56.0 to 19.4) |
−34.8 (−59.6 to 9.1) |
1,965,116 (1,769,448 to 2,214,210) |
−68.0 (−70.6 to −65.5) |
−28.4 (−33.6 to −22.1) |
|
| High–middle SDI | 9,656,432 (8,011,615 to 11,122,816) |
−61.2 (−66.5 to −56.1) |
−39.1 (−46.5 to −31.3) |
508,129 (285,413 to 777,826) |
— | −27.5 (−45.6 to 0.8) |
1,823,912 (961,776 to 3,188,864) |
227.0 (28.0 to 905.4) |
−46.7 (−64.4 to −12.9) |
11,988,473 (1,087,9230 to 13,089,954) |
−52.3 (−55.4 to −48.9) |
−40.0 (−44.4 to −35.4) |
|
| Middle SDI | 34,089,012 (30,391,151 to 37,561,252) |
−60.2 (−63.7 to −56.9) |
−35.3 (−40.7 to −29.5) |
297,278 (142,144 to 539,010) |
— | −14.5 (−45.3 to 25.5) |
2,672,977 (1,058,878 to 5,048,207) |
93.4 (−17.2 to 495.5) |
−39.2 (−65.9 to 4.9) |
37,059,267 (3,404,6223 to 40,091,006) |
−57.3 (−59.7 to −54.3) |
−35.5 (−39.7 to −30.6) |
|
| Low–middle SDI | 105,034,556 (87,174,675 to 121,173,835) |
−57.0 (−62.2 to −51.8) |
−31.6 (−40.6 to −22.5) |
668,617 (221,464 to 1,426,008) |
— | 15.5 (−42.9 to 110.7) |
11,779,956 (3,784,100 to 26,265,593) |
811.7 (211.1 to 2,792.2) |
−17.9 (−63.4 to 60.1) |
117,483,128 (104,647,935 to 130,986,372) |
−53.0 (−57.0 to −48.4) |
−30.3 (−36.9 to −23.0) |
|
| Low SDI | 181,931,292 (157,033,169 to 2,099,424,78) |
−48.4 (−53.1 to −42.7) |
−31.3 (−37.9 to −24.1) |
447,550 (168,786 to 916,468) |
— | 18.9 (−37.2 to 127.3) |
15,935,638 (6,985,776 to 28,018,760) |
922.7 (406.2 to 1910.8) |
−17.4 (−46.0 to 33.7) |
198,314,481 (175,760,628 to 227,715,901) |
−44.8 (−48.9 to −39.2) |
−30.3 (−36.6 to −23.7) |
|
| High–income | 1,365,328 (1,251,503 to 1,473,973) |
−74.6 (−75.8 to −73.4) |
−25.3 (−28.0 to −22.4) |
9,890 (4,205 to 20,051) |
— | 5.9 (−31.1 to 71.8) |
39,429 (17,676 to 81,357) |
−52.2 (−72.8 to −17.1) |
−31.8 (−55.4 to 9.9) |
1,414,647 (1,313,602 to 1,517,534) |
−74.1 (−75.2 to −73.0) |
−25.3 (−27.4 to −22.8) |
|
| High–income North America | 533,216 (485,434 to 582,727) |
−70.5 (−72.2 to −68.5) |
−8.3 (−12.6 to −4.4) |
3,442 (1,125 to 8,315) |
— | 45.4 (−33.3 to 189.6) |
13,737 (4,796 to 32,873) |
−88.4 (−93.0 to −78.8) |
−7.3 (−57.4 to 84.4) |
550,394 (505,799 to 598,674) |
−71.5 (−72.8 to −70.0) |
−8.1 (−11.4 to −4.8) |
|
| Australasia | 525,608 (429,935 to 634,807) |
−59.7 (−63.8 to −55.6) |
−13.7 (−24.7 to −2.2) |
6,997 (2,364 to 16,116) |
— | 105.1 (−26.5 to 440.4) |
28,770 (10,269 to 63,003) |
22.9 (−63.4 to 366.0) |
31.9 (−53.0 to 249.6) |
561,374 (470,595 to 673,032) |
−58.5 (−62.2 to −54.3) |
−11.5 (−20.3 to −0.4) |
|
| High–income Asia Pacific | 2,674,148 (2,402,789 to 2,920,938) |
−79.7 (−81.2 to −78.4) |
−33.7 (−38.0 to −29.5) |
15,325 (2,829 to 51,088) |
— | −9.3 (−73.8 to 131.2) |
60,475 (11,867 to 191,002) |
−57.4 (−88.5 to 83.8) |
−41.7 (−83.1 to 48.5) |
2,749,948 (2,508,546 to 2,983,379) |
−79.4 (−80.6 to −78.2) |
−33.8 (−37.2 to −30.2) |
|
| Western Europe | 858,780 (778,328 to 945,557) |
−71.6 (−73.0 to −70.1) |
−26.6 (−29.8 to −23.3) |
8,772 (4,073 to 17,054) |
— | 10.6 (−22.0 to 55.1) |
35,593 (17,467 to 66,028) |
−25.5 (−56.0 to 30.8) |
−28.5 (−49.4 to 0.4) |
903,144 (828,704 to 986,257) |
−70.7 (−72.0 to −69.3) |
−26.4 (−29.4 to −23.3) |
|
| Southern Latin America | 5,086,566 (4,565,267 to 5,581,735) |
−69.7 (−71.6 to −67.7) |
−21.4 (−28.4 to −14.5) |
33,196 (7,214 to 108,697) |
— | −3.7 (−66.1 to 151.1) |
129,996 (29,615 to 412,271) |
38.4 (−62.0 to 566.5) |
−37.9 (−78.2 to 61.6) |
5,249,758 (4,838,940 to 5,692,082) |
−68.8 (−70.3 to −67.1) |
−21.8 (−27.3 to −15.8) |
|
| Central Europe, Eastern Europe, and Central Asia | 11,592,264 (8,482,904 to 14,534,708) |
−22.1 (−42.4 to −4.0) |
−44.7 (−53.9 to −35.2) |
227,6718 (1,318,449 to 3,426,821) |
— | −17.0 (−35.9 to 10.8) |
5,172,251 (3,195,930 to 7,354,642) |
2,174.6 (964.8 to 4, 890.3) |
−47.8 (−59.8 to −30.5) |
19,041,233 (17,388,589 to 20,780,727) |
23.0 (19.4 to 27.6) |
−43.4 (−47.8 to −38.8) |
|
| Eastern Europe | 11,754,739 (7,752,734 to 15862,953) |
5.1 (−27.8 to 35.8) |
−50.8 (−62.4 to −36.1) |
2,871,273 (1,627,275 to 4,347,025) |
— | −16.1 (−39.9 to 23.4) |
6,539,035 (3,880,816 to 9,664,468) |
1925.1 (715.6 to 5394.4) |
−47.1 (−62.3 to −22.8) |
21,165,047 (18,898,229 to 23,668,148) |
70.0 (64.7 to 81.6) |
−46.7 (−52.6 to −40.6) |
|
| Central Europe | 4,249,250 (3,663,795 to 4,820,303) |
−55.9 (−59.2 to −53.4) |
−37.8 (−46.0 to −29.3) |
78,787 (29,413 to 166,328) |
— | −15.8 (−70.2 to 123.9) |
178,828 (68,097 to 382,136) |
73.8 (−29.5 to 329.9) |
−47.2 (−81.2 to 39.9) |
4,506,865 (3,949,646 to 5,117,948) |
−53.7 (−55.4 to −51.8) |
−38.0 (−45.3 to −30.2) |
|
| Central Asia | 19,543,646 (13,662,140 to 25,002,920) |
−43.3 (−57.8 to −29.7) |
−38.8 (−51.4 to −23.3) |
3,562,648 (1,929,378 to 5,746,708) |
— | −23.5 (−47.3 to 5.7) |
8,051,066 (4,607,795 to 12,155,328) |
7,854.0 (3,041.9 to 26,277.3) |
−52.1 (−66.9 to −34.1) |
31,157,360 (27,790,597 to 35,046,387) |
−5.6 (−9.2 to −1.4) |
−41.7 (−47.5 to −35.0) |
|
| Latin America and Caribbean | 10,979,950 (9,439,112 to 12,617,838) |
−74.0 (−75.9 to −72.1) |
−28.4 (−35.6 to −19.7) |
116,022 (46,765 to 236,294) |
— | 10.1 (−29.4 to 66.5) |
724,032 (305,884 to 1,462,396) |
119.9 (−1.0 to 424.2) |
−27.7 (−53.7 to 8.7) |
11,820,004 (10425048 to 13,425,278) |
−72.3 (−73.8 to −70.6) |
−28.1 (−35.3 to −19.7) |
|
| Central Latin America | 7,966,157 (6,664,474 to 9,424,585) |
−77.1 (−78.6 to −75.7) |
−21.8 (−33.0 to −8.4) |
74,611 (25,510 to 172,152) |
— | 22.6 (−39.6 to 132.7) |
467,048 (165,144 to 1,085,389) |
402.9 (107.1 to 1,264.3) |
−19.4 (−60.4 to 51.7) |
8,507,816 (7,272,120 to 10,018,707) |
−75.7 (−76.8 to −74.5) |
−21.4 (−32.0 to −8.7) |
|
| Andean Latin America | 23,164,834 (17,515,269 to 29468116) |
−82.1 (−85.0 to −79.0) |
−41.5 (−53.3 to −27.9) |
482,303 (167,515 to 1,026,341) |
— | −13.6 (−51.5 to 50.7) |
3,001,873 (1,158,458 to 6,275,897) |
44.9 (−46.8 to 410.1) |
−43.3 (−68.3 to −1.8) |
26,649,010 (21,309,186 to 33,069,045) |
−79.7 (−82.3 to −76.8) |
−41.4 (−53.0 to −28.9) |
|
| Caribbean | 22,807,329 (18,287,742 to 29,009,686) |
−54.1 (−61.7 to −44.9) |
−11.3 (−24.5 to 5.4) |
37,643 (7,725 to 120,555) |
— | 105.9 (−33.6 to 622.4) |
232,306 (51,572 to 741,040) |
−59.5 (−89.9 to 74.9) |
33.9 (−56.6 to 357.8) |
23,077,279 (18,630,886 to 29,226,489) |
−54.1 (−61.7 to −45.0) |
−10.9 (−23.9 to 5.5) |
|
| Tropical Latin America | 8,607,012 (7,496,690 to 9,408,760) |
−65.6 (−68.1 to −63.4) |
−31.9 (−38.9 to −26.4) |
80,462 (13,334 to 232,007) |
— | 35.3 (−62.7 to 226.6) |
502,935 (95,276 to 1,371,378) |
1,329.1 (223.4 to 10,666.9) |
−11.3 (−75.7 to 114.2) |
9,190,409 (8,653,034 to 9,806,860) |
−63.9 (−65.8 to −62.1) |
−30.7 (−34.1 to −26.7) |
|
| Southeast Asia, East Asia, and Oceania | 27,721,911 (24,998,776 to 30,485,228) |
−65.0 (−68.1 to −61.4) |
−35.9 (−41.5 to −29.3) |
222,866 (93,163 to 470,337) |
— | −24.0 (−55.3 to 25.4) |
1,224,305 (555,745 to 2,413,379) |
−24.9 (−70.7 to 142.9) |
−50.0 (−70.9 to −17.3) |
29,169,082 (26,653,071 to 31,884,461) |
−63.8 (−66.5 to −60.6) |
−36.6 (−41.7 to −30.7) |
|
| East Asia | 7,613,119 (6,188,762 to 9,041,545) |
−80.6 (−83.6 to −77.3) |
−41.4 (−49.8 to −32.0) |
95,393 (20,783 to 270,768) |
— | −37.9 (−81.0 to 52.4) |
551,961 (129,122 to 1,501,930) |
−66.5 (−88.2 to 43.1) |
−58.2 (−87.1 to 2.1) |
8,260,473 (7,130,296 to 9,642,073) |
−79.6 (−82.0 to −77.0) |
−42.9 (−49.2 to −35.7) |
|
| Southeast Asia | 79,921,750 (71,686,540 to 8,8512,449) |
−57.2 (−61.7 to −52.0) |
−36.1 (−42.7 to −28.4) |
550,895 (220,139 to 1,187,069) |
— | −18.7 (−54.6 to 43.3) |
2,950,391 (1,277,201 to 6,064,725) |
305.3 (54.6 to 1162.0) |
−46.9 (−70.5 to −5.9) |
83,423,036 (75,109,968 to 92,043,542) |
−55.3 (−59.6 to −50.3) |
−36.4 (−42.7 to −29.3) |
|
| Oceania | 72,522,825 (51,687,644 to 96,117,455) |
−34.4 (−43.5 to −23.8) |
−25.8 (−37.2 to −13.2) |
930,510 (222,124 to 2,399,806) |
— | 227.3 (−15.3 to 1157.5) |
4,957,693 (1,224,164 to 1,252,1788) |
1,502.6 (300.7 to 7,255.0) |
112.1 (−45.3 to 711.1) |
78,411,028 (55,989,827 to 10,439,6559) |
−32.7 (−41.7 to −21.7) |
−21.9 (−32.6 to −9.9) |
|
| North Africa and Middle East | 10,938,453 (8,928,694 to 13,286,644) |
−64.5 (−69.2 to −57.0) |
−36.4 (−43.0 to −27.6) |
50,896 (18,133 to 111,731) |
— | −14.1 (−53.9 to 64.2) |
708,928 (279,633 to 1,553,081) |
633.3 (251.2 to 1,406.6) |
−43.0 (−69.0 to 8.3) |
11,698,277 (9,679,327 to 14092394) |
−61.9 (−66.4 to −54.4) |
−36.8 (−42.3 to −27.9) |
|
| South Asia | 106,259,629 (84,804,062 to 124,786,790) |
−60.3 (−65.8 to −54.7) |
−32.8 (−43.7 to −21.0) |
726,544 (179,676 to 1,714,811) |
— | 21.5 (−53.4 to 152.2) |
1,442,9579 (3,622,339 to 33,497,063) |
2,088.2 (445.5 to 11,503.1) |
−19.3 (−69.1 to 69.1) |
121,415,751 (107,635,515 to 137,204,601) |
−55.8 (−59.8 to −50.8) |
−31.3 (−39.2 to −22.1) |
|
| Sub–Saharan Africa | 209,666,954 (179,686,586 to 243,717,359) |
−41.3 (−46.4 to −35.2) |
−32.1 (−39.1 to −24.8) |
205,302 (86,281 to 397,275) |
— | 19.1 (−13.4 to 66.9) |
15,297,529 (7,062,894 to 27,182,866) |
793.0 (395.8 to 1,491.4) |
−20.5 (−42.3 to 11.1) |
225,169,785 (196,603,360 to 259,821,718) |
−37.9 (−42.6 to −32.1) |
−31.4 (−38.2 to −24.3) |
|
| Southern Sub–Saharan Africa | 193,731,974 (16,7462,698 to 219,891,304) |
5.6 (−11.0 to 23.5) |
−41.4 (−47.3 to −34.5) |
210,923 (72,097 to 493,198) |
— | −9.9 (−56.2 to 97.3) |
15,768,923 (5,637,570 to 32,943,763) |
893.6 (209.9 to 4,339.5) |
−39.4 (−70.8 to 31.3) |
209,711,820 (186,844,567 to 233,887,784) |
13.0 (−2.6 to 31.1) |
−41.3 (−46.3 to −35.5) |
|
| Western Sub–Saharan Africa | 146,451,589 (119,644,604 to 175,356,045) |
−44.7 (−53.8 to −34.1) |
−26.1 (−37.4 to −14.0) |
136,381 (47,579 to 309,964) |
— | 6.9 (−40.5 to 89.7) |
10,213,312 (3,669,096 to 21,324,858) |
571.5 (239.1 to 1,320.0) |
−28.6 (−60.3 to 26.8) |
156,801,283 (131,487,103 to 187,162,945) |
−41.0 (−50.3 to −30.2) |
−26.3 (−36.8 to −15.1) |
|
| Eastern Sub–Saharan Africa | 252,389,897 (210,268,128 to 297,240,990) |
−49.6 (−55.3 to −43.4) |
−31.2 (−38.0 to −24.0) |
274,597 (115,496 to 559,228) |
— | 38.2 (−10.8 to 111.2) |
20,415,191 (8,886,884 to 39,007,962) |
1,588.0 (578.6 to 4,040.5) |
−7.8 (−40.5 to 41.0) |
273,079,684 (232,125,392 to 317,441,640) |
−46.6 (−52.2 to −40.5) |
−29.8 (−36.1 to −23.2) |
|
| Central Sub–Saharan Africa | 323,076,125 (254,165,463 to 419,281,016) |
−28.1 (−39.8 to −14.5) |
−36.8 (−48.2 to −24.8) |
239,338 (48,121 to 729,088) |
— | 21.0 (−56.9 to 234.5) |
17,788,355 (3,873,758 to 57,171,430) |
382.4 (−2.8 to 2,290.0) |
−19.4 (−71.2 to 123.0) |
341,103,817 (269,445,333 to 438,643,029) |
−25.4 (−37.1 to −11.7) |
−36.1 (−46.9 to −24.6) |
|