Table 3.
Deaths of major HIV–negative individuals in 2019, and change of age–standardized deaths during the periods 1990–2010 and 2010–2019 for both sexes.
| Group | Drug–susceptible tuberculosis | Extensively drug–resistant tuberculosis | Multidrug–resistant tuberculosis without extensive drug resistance | Tuberculosis | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of deaths, 2019 | Annualized rate of change of age–standardized incidence | Number of deaths, 2019 | Annualized rate of change of age–standardized incidence | Number of deaths, 2019 | Annualized rate of change of age–standardized incidence | Number of deaths, 2019 | Annualized rate of change of age–standardized incidence | |||||
| 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | 1990–2010 | 2010–2019 | |||||
| Global | 1,317,296 (1,147,331 to 1,473,409) |
−53.0 (−57.3 to −48.3) |
−29.4 (−36.3 to −22.3) |
10,419 (4901 to 18734) |
— | −5.6 (−32.8 to 37.6) |
135,906 (54,012 to 258,625) |
348.4 (114.3 to 929.2) |
−21.6 (−52.4 to 27.5) |
1,463,621 (1,339,240 to 1,602,711) |
−48.9 (−52.0 to −44.4) |
−28.6 (−34.4 to −22.2) |
| High SDI | 67,262 (59,261 to 74,320) |
−67.8 (−70.3 to −65.5) |
−24.4 (−28.9 to −19.1) |
661 (287 to 1326) |
— | 2.1 (−30.0 to 51.3) |
2,798 (1,152 to 5,487) |
−33.3 (−58.8 to 10.8) |
−31.0 (−54.8 to 8.1) |
70,722 (62,719 to 77,388) |
−66.8 (−69.2 to −64.8) |
−24.5 (−28.6 to −19.8) |
| High–middle SDI | 226,851 (186,851 to 259,473) |
−64.3 (−69.6 to −59.4) |
−38.4 (−46.1 to −30.0) |
12,425 (6,810 to 19,394) |
— | −26.0 (−44.2 to 2.3) |
44,025 (22,300 to 77,554) |
171.3 (2.9 to 755.1) |
−45.6 (−63.7 to −10.5) |
283,301 (261,676 to 307,145) |
−56.1 (−59.1 to −52.6) |
−39.2 (−44.0 to −34.2) |
| Middle SDI | 976,867 (877,622 to 1,087,632) |
−60.7 (−64.3 to −56.8) |
−36.5 (−42.0 to −30.2) |
8,988 (3,931 to 16,609) |
— | −16.1 (−46.6 to 25.3) |
79,109 (29,736 to 148,793) |
86.5 (−18.4 to 454.3) |
−39.6 (−65.5 to 0.9) |
1,064,964 (986,626 to 1,165,682) |
−57.8 (−60.7 to −53.9) |
−36.7 (−40.9 to −31.5) |
| Low–middle SDI | 3,027,314 (2,490,850 to 3,494,543) |
−57.9 (−63.3 to −52.3) |
−30.8 (−40.4 to −20.5) |
20,786 (6,453 to 45,487) |
— | 18.0 (−43.7 to 118.5) |
357,339 (108,036 to 799,780) |
811.8 (214.5 to 2,823.3) |
−16.5 (−63.2 to 64.1) |
3,405,439 (3,010,264 to 3,859,166) |
−53.8 (−58.1 to −48.4) |
−29.4 (−37.1 to −21.2) |
| Low SDI | 5,472,994 (4,760,874 to 6,280,801) |
−47.3 (−52.1 to −40.1) |
−30.5 (−37.2 to −23.1) |
15,018 (5,331 to 31,846) |
— | 25.5 (−36.6 to 147.8) |
506,356 (209,116 to 921,183) |
965.5 (434.6 to 1,966.7) |
−15.1 (−45.6 to 39.0) |
5,994,367 (5,330,137 to 6,846,309) |
−43.4 (−47.7 to −36.8) |
−29.3 (−35.7 to −22.0) |
| High–income | 55,620 (49,348 to 59,943) |
−69.8 (−71.9 to −68.5) |
−22.0 (−25.4 to −18.5) |
448 (175 to 946) |
— | 12.7 (−29.2 to 84.8) |
16,99 (667 to 3,632) |
−45.4 (−67.0 to −4.3) |
−27.9 (−54.7 to 18.2) |
57,767 (51,199 to 61,873) |
−69.2 (−71.1 to −67.9) |
−22.0 (−24.9 to −19.0) |
| High–income North America | 17,825 (16,352 to 18,996) |
−71.6 (−73.1 to −69.7) |
−5.7 (−10.4 to −1.1) |
135 (42 to 328) |
— | 46.7 (−31.5 to 188.9) |
511 (168 to 1,200) |
−88.2 (−93.0 to −78.7) |
−6.2 (−56.2 to 84.8) |
18,471 (17,200 to 19,421) |
−72.6 (−73.6 to −71.5) |
−5.4 (−9.0 to −1.6) |
| Australasia | 19,915 (15,627 to 24,956) |
−60.4 (−65.0 to −55.9) |
−12.2 (−25.7 to 3.4) |
336 (106 to 786) |
— | 113.1 (−26.5 to 492.6) |
1,279 (406 to 2,958) |
31.4 (−58.6 to 397.9) |
36.6 (−53.0 to 279.2) |
21,531 (17,482 to 26,434) |
−59.0 (−63.0 to −54.6) |
−9.4 (−21.7 to 5.3) |
| High–income Asia Pacific | 127,176 (108,521 to 140,684) |
−73.7 (−76.3 to −71.9) |
−28.7 (−33.3 to −24.4) |
773 (137 to 2465) |
— | 1.7 (−68.9 to 159.0) |
2,931 (563 to 8,561) |
−48.3 (−85.5 to 101.7) |
−35.0 (−80.1 to 65.7) |
130,880 (112,363 to 143,490) |
−73.3 (−75.7 to −71.7) |
−28.8 (−32.2 to −25.0) |
| Western Europe | 33,983 (30,329 to 36,885) |
−71.3 (−72.8 to −69.8) |
−25.1 (−29.5 to −20.4) |
418 (181 to 847) |
— | 13.5 (−21.7 to 59.4) |
1,584 (698 to 3,101) |
−17.9 (−51.6 to 40.4) |
−27.4 (−49.9 to 2.0) |
35,985 (32,289 to 38,566) |
−70.2 (−71.6 to −68.9) |
−24.9 (−29.0 to −20.7) |
| Southern Latin America | 149,755 (134,830 to 162,766) |
−68.2 (−70.2 to −66.2) |
−21.6 (−28.6 to −14.2) |
1,053 (248 to 3,259) |
— | −1.9 (−64.4 to 136.8) |
4,003 (997 to 12,092) |
46.2 (−58.5 to 549.3) |
−36.9 (−77.2 to 51.5) |
154,811 (143,088 to 167,740) |
−67.2 (−68.8 to −65.4) |
−22.0 (−27.8 to −15.6) |
| Central Europe, Eastern Europe, and Central Asia | 239,788 (166,733 to 304,989) |
−27.3 (−47.4 to −9.2) |
−44.9 (−54.5 to −34.3) |
50,867 (28,928 to 77,287) |
— | −15.9 (−35.5 to 13.0) |
111,080 (65,478 to 160,237) |
1,839.5 (812.1 to 4,167.6) |
−47.6 (−59.9 to −29.8) |
401,735 (366,858 to 439,255) |
16.1 (13.2 to 21.2) |
−43.2 (−48.1 to −38.0) |
| Eastern Europe | 245,360 (151,499 to 339,703) |
−4.8 (−36.6 to 25.1) |
−51.0 (−63.8 to −34.9) |
66,648 (36,789 to 101,647) |
— | −15.0 (−38.9 to 24.2) |
145,643 (83,153 to 219,320) |
1,710.5 (646.4 to 4,723.3) |
−47.0 (−62.1 to −22.8) |
457,652 (402,407 to 517,082) |
57.8 (52.8 to 68.9) |
−46.4 (−52.9 to −39.5) |
| Central Europe | 111,364 (96,464 to 127,628) |
−60.0 (−63.0 to −57.8) |
−36.9 (−45.2 to −27.7) |
2,109 (792 to 4,440) |
— | −15.7 (−68.2 to 108.9) |
4,616 (1,719 to 10,014) |
69.0 (−28.2 to 289.3) |
−47.3 (−80.3 to 29.8) |
118,088 (102,308 to 133,859) |
−58.0 (−59.3 to −56.3) |
−37.1 (−45.1 to −28.7) |
| Central Asia | 407,026 (268,228 to 533,068) |
−42.5 (−59.1 to −26.9) |
−37.9 (−51.5 to −20.7) |
82,029 (43,857 to 133,860) |
— | −21.6 (−45.7 to 7.5) |
178,817 (100,017 to 274,260) |
7,803.1 (2,987.1 to 26,971.3) |
−51.2 (−66.2 to −33.2) |
667,872 (596,064 to 755,204) |
−1.5 (−5.0 to 2.7) |
−40.7 (−47.3 to −33.2) |
| Latin America and Caribbean | 281,371 (242,462 to 322,727) |
−73.8 (−75.7 to −71.9) |
−29.2 (−36.9 to −20.2) |
3,359 (1,342 to 6,864) |
— | 11.0 (−28.7 to 68.9) |
20,295 (8,326 to 41,956) |
146.7 (12.2 to 475.0) |
−27.6 (−53.7 to 9.7) |
305,025 (269,127 to 346,499) |
−71.9 (−73.3 to −70.3) |
−28.8 (−35.8 to −20.1) |
| Central Latin America | 223,839 (184,989 to 266,927) |
−78.2 (−79.6 to −76.9) |
−22.9 (−34.6 to −8.9) |
2,316 (772 to 5,388) |
— | 22.4 (−38.5 to 128.7) |
14,035 (4,851 to 32,591) |
412.4 (111.0 to 1,341.2) |
−20.0 (−60.0 to 48.5) |
240,190 (205,693 to 283,352) |
−76.8 (−77.7 to −75.7) |
−22.5 (−33.5 to −9.1) |
| Andean Latin America | 624,191 (470,040 to 792,892) |
−80.8 (−84.2 to −77.5) |
−39.8 (−52.8 to −25.2) |
14,253 (4,888 to 30,166) |
— | −10.6 (−49.9 to 52.5) |
86,109 (32,036 to 179,472) |
63.0 (−40.7 to 457.5) |
−41.6 (−67.5 to −1.0) |
72,4554 (575,397 to 901,576) |
−78.1 (−81.0 to −75.0) |
−39.6 (−51.6 to −26.2) |
| Caribbean | 465,542 (372,093 to 587,816) |
−53.7 (−61.2 to −44.4) |
−12.0 (−24.9 to 4.8) |
863 (189 to 2,667) |
— | 101.1 (−31.2 to 549.7) |
5,173 (1,169 to 15,725) |
−57.9 (−88.3 to 66.5) |
30.8 (−55.3 to 322.1) |
471,578 (377,189 to 593,127) |
−53.7 (−61.2 to −44.2) |
−11.6 (−24.5 to 5.5) |
| Tropical Latin America | 219,804 (189,629 to 240,003) |
−64.0 (−66.5 to −61.9) |
−32.7 (−40.0 to −27.0) |
2,278 (382 to 6,614) |
— | 35.5 (−62.7 to 225.6) |
13,738 (2,587 to 38,203) |
1,416.6 (249.9 to 10,740.6) |
−11.9 (−75.8 to 111.5) |
235,820 (222,893 to 249,304) |
−62.2 (−63.6 to −60.4) |
−31.5 (−34.7 to −27.4) |
| Southeast Asia, East Asia, and Oceania | 771,555 (697,343 to 852,161) |
−65.4 (−68.8 to −61.6) |
−38.6 (−44.0 to −31.6) |
7,177 (2,860 to 15,216) |
— | −25.5 (−55.3 to 20.3) |
37,502 (16,030 to 75,935) |
−21.9 (−69.3 to 146.2) |
−51.7 (−71.1 to −22.2) |
816,234 (746,042 to 890,269) |
−64.0 (−67.0 to −60.4) |
−39.2 (−44.5 to −33.5) |
| East Asia | 193,491 (153,881 to 229,273) |
−81.6 (−84.6 to −78.2) |
−44.5 (−54.6 to −33.1) |
3,136 (685 to 8,749) |
— | −37.1 (−80.8 to 52.7) |
16,405 (3,650 to 45,583) |
−65.4 (−87.8 to 44.3) |
−59.2 (−87.6 to −1.2) |
213,033 (184,453 to 244,465) |
−80.4 (−82.9 to −77.5) |
−45.9 (−53.6 to −37.0) |
| Southeast Asia | 257,9881 (2,302,945 to 2,850,244) |
−54.6 (−59.7 to −48.5) |
−36.8 (−43.1 to −29.0) |
19,804 (7,810 to 42,049) |
— | −18.6 (−53.9 to 41.0) |
103,422 (44,149 to 212,575) |
308.1 (60.4 to 1,128.1) |
−47.3 (−70.2 to −8.8) |
2,703,107 (2,435,044 to 2,965,429) |
−52.4 (−57.2 to −46.4) |
−37.2 (−43.2 to −30.4) |
| Oceania | 1,994,397 (1,357,173 to 2,679,431) |
−36.1 (−45.5 to −25.4) |
−25.4 (−37.4 to −12.3) |
26,734 (6,233 to 69,366) |
— | 230.3 (−13.8 to 1,139.2) |
139,813 (32,711 to 349,128) |
1,441.7 (289.3 to 6,615.2) |
113.6 (−44.2 to 701.8) |
2,160,944 (1,471,698 to 2,891,979) |
−34.4 (−43.9 to −23.4) |
−21.4 (−31.5 to −9.2) |
| North Africa and Middle East | 320,544 (263,822 to 399,027) |
−64.7 (−69.7 to −54.6) |
−36.7 (−43.4 to −25.3) |
1,582 (567 to 3,403) |
— | −11.2 (−50.9 to 57.3) |
21,266 (8,193 to 45,911) |
603.4 (234.1 to 1,367.3) |
−41.5 (−67.7 to 3.7) |
343,392 (285,529 to 423,277) |
−62.2 (−67.3 to −51.7) |
−36.9 (−42.8 to −25.2) |
| South Asia | 3,119,395 (2,427,290 to 3,725,829) |
−61.4 (−67.1 to −55.3) |
−32.5 (−44.4 to −19.0) |
22,997 (5,435 to 55,147) |
— | 23.8 (−53.2 to 157.0) |
445,982 (106,308 to 1,047,464) |
2,077.1 (438.4 to 11,498.4) |
−18.2 (−69.0 to 70.0) |
3,588,374 (3,145,779 to 4,126,190) |
−56.8 (−60.9 to −50.9) |
−30.8 (−39.4 to −20.3) |
| Sub–Saharan Africa | 6,420,272 (5,575,936 to 7,434,606) |
−39.4 (−45.0 to −32.4) |
−30.6 (−37.5 to −23.6) |
6,618 (2,753 to 12,825) |
— | 21.7 (−11.2 to 71.3) |
486,964 (218,898 to 865,752) |
859.0 (454.6 to 1,583.1) |
−18.9 (−41.0 to 14.0) |
6,913,854 (6,078,443 to 7,951,553) |
−35.7 (−41.1 to −29.2) |
−29.8 (−36.1 to −23.2) |
| Southern Sub–Saharan Africa | 5,023,801 (4,382,100 to 5,666,017) |
14.1 (−4.3 to 35.6) |
−41.7 (−47.7 to −35.3) |
5,716 (1,921 to 13,631) |
— | −10.3 (−56.8 to 96.3) |
420,136 (149,748 to 904,445) |
987.1 (237.1 to 4,612.5) |
−40.0 (−71.2 to 30.6) |
5,449,653 (4,928,930 to 6,011,006) |
22.4 (4.7 to 45.2) |
−41.5 (−46.3 to −36.3) |
| Western Sub–Saharan Africa | 4,751,910 (3,841,820 to 5,771,344) |
−43.7 (−53.2 to −31.4) |
−25.1 (−36.0 to −13.5) |
4,802 (1,651 to 11,058) |
— | 9.3 (−39.5 to 96.7) |
353,882 (123,347 to 753,343) |
639.3 (265.1 to 1,429.2) |
−27.1 (−59.8 to 30.9) |
5,110,594 (4,280,088 to 6,148,863) |
−39.7 (−49.6 to −27.3) |
−25.2 (−35.1 to −14.8) |
| Eastern Sub–Saharan Africa | 7,894,787 (6,579,176 to 9,346,079) |
−48.1 (−53.9 to −40.9) |
−30.8 (−37.0 to −23.9) |
8,842 (3,625 to 18,055) |
— | 40.3 (−7.5 to 115.6) |
650,554 (281,043 to 1,262,596) |
1,594.5 (591.8 to 4,082.2) |
−6.6 (−38.4 to 43.4) |
8,554,184 (7,290,283 to 9,901,313) |
−45.1 (−50.7 to −38.2) |
−29.3 (−35.0 to −22.5) |
| Central Sub–Saharan Africa | 9,577,194 (7,420,478 to 12,726,686) |
−22.6 (−35.1 to −6.9) |
−33.9 (−45.8 to −21.3) |
7,490 (1,472 to 23,347) |
— | 29.2 (−55.1 to 247.5) |
550,241 (115,859 to 1,811,878) |
420.4 (4.0 to 2,530.1) |
−14.2 (−70.1 to 131.1) |
10,134,925 (7,919,764 to 13,250,791) |
−19.6 (−32.0 to −3.7) |
−33.1 (−44.7 to −20.6) |