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. 2022 Jul 22;13:924747. doi: 10.3389/fphar.2022.924747

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Copyright © 2022 Li, Cui, Fan, Lu, Ai, Liu, Liu, Du, Qin, Sun, Yu, Liu and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Searching and screening process: literature search and study selection Through the initial search, we retrieved a total of 3,808 records from PubMed, Web of Science, and Cochrane Library. After examining the titles and abstracts, 250 studies were selected for further full-text scrutiny. In all, 207 studies were excluded due to the following reasons: sample overlap with other studies (n = 80), no necessary sample data (n = 45), other outcomes (n = 27), other stroke (n = 20), other language (n = 17), no placebo group (n = 11), and mild cognitive impairment (n = 7).