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. 2022 Jul 22;13:924747. doi: 10.3389/fphar.2022.924747

TABLE 6.

Results of pairwise meta-analyses for NFDs.

Comparative medication Reference medication Number of studies Pairwise meta-analyses
Number of control Number of patients MD/OR/RR 95% CI I2 P
XNJ Placebo 13 356 347 −3.78 [−4.75, −2.81] 54 0.00001
NST Placebo 13 100 100 8.15 [10.11, 49.10] 95 0.0005
Chuanxiong Placebo 3 80 81 −3.11 [−5.22, −1.00] 0 0.0039
Safflower yellow Placebo 7 368 394 3.11 [2.06, 4.68] 0 0.00001
Rhubarb Placebo 12 210 210 −3.36 [−6.10, −0.62] 89 0.00001
Puerarin Placebo 16 659 699 −3.69 [−4.67, −2.71] 70 0.00001
Albumin Placebo 4 804 807 1.04 [0.85, 1.27] 0 0.65
Salvianolic acids Placebo 12 235 235 −8.65 [−11.10, −6.20] 31 0.001
Pntsp Placebo 20 1464 1435 −3.36 [−4.20, −2.53] 74 0.0001
Nimodipine Placebo 8 677 806 0.54 [0.50, 0.78] NA 0.0001
HUK Placebo 9 338 338 1.30 [1.21, 1.41] 0 0.00001
DZSM Placebo 5 341 340 −2.81 [−4.17, −1.44] 85.9 0.1
Mailuoning Placebo 15 736 755 0.31 [0.23, 0.42] 0 0.001
TNK Placebo 4 656 671 1.56 [1.0, 2.43] 0 0.05
MLC601 Placebo 2 275 520 0.27 [−0.02, 0.55] 66 0.06

CI, confidence interval; MD, mean difference; OR, risk ratio; I2, heterogeneity, NST, NaoShuanTong capsule; XNJ, Xingnaojing capsule; Pntsp, Panax notoginseng Saponin; TQHX, Tongqiao Huoxue decoction; TNK, tenecteplase.