TABLE 6.
Comparative medication | Reference medication | Number of studies | Pairwise meta-analyses | |||||
---|---|---|---|---|---|---|---|---|
Number of control | Number of patients | MD/OR/RR | 95% CI | I2 | P | |||
XNJ | Placebo | 13 | 356 | 347 | −3.78 | [−4.75, −2.81] | 54 | 0.00001 |
NST | Placebo | 13 | 100 | 100 | 8.15 | [10.11, 49.10] | 95 | 0.0005 |
Chuanxiong | Placebo | 3 | 80 | 81 | −3.11 | [−5.22, −1.00] | 0 | 0.0039 |
Safflower yellow | Placebo | 7 | 368 | 394 | 3.11 | [2.06, 4.68] | 0 | 0.00001 |
Rhubarb | Placebo | 12 | 210 | 210 | −3.36 | [−6.10, −0.62] | 89 | 0.00001 |
Puerarin | Placebo | 16 | 659 | 699 | −3.69 | [−4.67, −2.71] | 70 | 0.00001 |
Albumin | Placebo | 4 | 804 | 807 | 1.04 | [0.85, 1.27] | 0 | 0.65 |
Salvianolic acids | Placebo | 12 | 235 | 235 | −8.65 | [−11.10, −6.20] | 31 | 0.001 |
Pntsp | Placebo | 20 | 1464 | 1435 | −3.36 | [−4.20, −2.53] | 74 | 0.0001 |
Nimodipine | Placebo | 8 | 677 | 806 | 0.54 | [0.50, 0.78] | NA | 0.0001 |
HUK | Placebo | 9 | 338 | 338 | 1.30 | [1.21, 1.41] | 0 | 0.00001 |
DZSM | Placebo | 5 | 341 | 340 | −2.81 | [−4.17, −1.44] | 85.9 | 0.1 |
Mailuoning | Placebo | 15 | 736 | 755 | 0.31 | [0.23, 0.42] | 0 | 0.001 |
TNK | Placebo | 4 | 656 | 671 | 1.56 | [1.0, 2.43] | 0 | 0.05 |
MLC601 | Placebo | 2 | 275 | 520 | 0.27 | [−0.02, 0.55] | 66 | 0.06 |
CI, confidence interval; MD, mean difference; OR, risk ratio; I2, heterogeneity, NST, NaoShuanTong capsule; XNJ, Xingnaojing capsule; Pntsp, Panax notoginseng Saponin; TQHX, Tongqiao Huoxue decoction; TNK, tenecteplase.