TABLE 7.
Comparative medication | Reference medication | Number of studies | Pairwise meta-analyses | |||||
---|---|---|---|---|---|---|---|---|
Number of control | Number of patients | MD/OR/RR | 95% CI | I2 | P | |||
Heparin | Placebo | 9 | 288 | 330 | 0.71 | [0.25, 2.05] | 32 | 0.22 |
Safflower yellow | Placebo | 7 | 368 | 394 | NA | NA | 0 | 0.93 |
Stent retrievers | Placebo | 5 | 652 | 634 | 1.08 | [0.64, 2.30] | 0 | 0.63 |
Ginkgo biloba | Placebo | 12 | 266 | 281 | 0.82 | [0.43, 1.57] | 0 | 0.443 |
Tirofiban | Placebo | 6 | 216 | 213 | 1.14 | [0.72, 1.82] | 0 | 0.57 |
Edaravone plus rt-PA | Placebo | 8 | 221 | 221 | 0.44 | [0.29, 0.66] | 0 | 0.93 |
Alpha 1 | Placebo | 6 | 467 | 595 | 1.25 | [0.97, 1.62] | 9 | 0.09 |
TNK | Placebo | 4 | 658 | 676 | 1.07 | [0.6, 1.93] | 0 | 0.81 |
MTE plus stent retrievers | Placebo | 5 | 146 | 144 | 0.59 | [0.35,0.97] | 0 | 0.83 |
MTE | Placebo | 5 | 141 | 140 | 3.05 | [0.44, 21.23] | 0 | 0.25 |
tPA plus MTE | Placebo | 7 | 2639 | 2640 | 0.93 | [0.72, 1.19] | 29 | 0.13 |
Cilostazol | Placebo | 6 | 1728 | 1731 | 0.29 | [0.15, 0.56] | 0 | 0.77 |
CI, confidence interval; MD, mean difference; OR, risk ratio; I2, heterogeneity, TNK, tenecteplase.