TABLE 9.
Results of pairwise meta-analyses for AE.
| Comparative medication | Reference medication | Number of studies | Pairwise meta-analyses | |||||
|---|---|---|---|---|---|---|---|---|
| Number of control | Number of patients | MD/OR/RR | 95% CI | I2 | P | |||
| Chuanxiong | Placebo | 3 | 50 | 49 | 1.02 | [0.35, 2.96] | NA | 0.09 |
| MSCs | Placebo | 5 | 64 | 44 | 0.43 | [0.18, 1.05] | 0 | 0.06 |
| Cerebrolysin | Placebo | 7 | 971 | 808 | 1.18 | [0.86, 1.64] | 23 | 0.27 |
| Ginkgo biloba | Placebo | 12 | 388 | 406 | 1.48 | [0.51, 2.71] | 54 | 0.07 |
| Stem cell-based therapy | Placebo | 9 | 136 | 139 | 2.59 | [0.11, 5.93] | 0 | 0.87 |
| TQHX plus XM | Placebo | 12 | 180 | 180 | 1.78 | [0.51, 6.2] | 0 | 0.36 |
| Salvianolic acids | Placebo | 12 | 1496 | 1498 | 1.45 | [1.11, 1.91] | 0 | 0.007 |
| Colchicine | Placebo | 4 | 2764 | 2788 | 0.31 | [0.13, 0.71] | 0 | 0.006 |
| NBP | Placebo | 4 | 108 | 108 | 3.55 | [1.19, 10.56] | 0 | < 0.05 |
| Pntsp | Placebo | 20 | 361 | 354 | 0.62 | [0.39, 0.97] | 0 | 0.04 |
| HUK | Placebo | 9 | 387 | 387 | 0.01 | [0.02, 0.04] | 0 | 0.50 |
| Mailuoning | Placebo | 2 | 64 | 65 | 1.39 | [0.28, 6.76] | 0 | 0.57 |
| cinepazide maleate | Placebo | NA | 648 | 643 | NA | NA | NA | 0.82 |
CI, confidence interval; MD, mean difference; OR, risk ratio; I2, heterogeneity; MSCs, Pntsp, Panax notoginseng Saponin; autologous bone marrow stromal cells; TQHX, Tongqiao Huoxue Decoction.