Table 12.
Catalase activity of A375 cells after 24 h and 72 h incubation with 20 nm and 100 nm Au NPs (pcs/mL).
| Control or pcs/mL | 24 h∗ Catalase activity (U/mg proteins) |
72 h Catalase activity (U/mg proteins) |
||
|---|---|---|---|---|
| Control • | 5.37 (5.37–5.75) | 2.2∗∗ (2.2–2.45) | ||
| 20 nm | 100 nm | 20 nm | 100 nm | |
| 1.6 × 107 | 3.27• (2.58–3.27) | 4.669 (4.16–5.05) | ||
| 1.6 × 109+ | 11.08 (11.08–11.46) | 5.05 (0.67–5.05) | 4.1∗ (3.78–4.29) | 11.58••• (11.33–11.77) |
| 1.6 × 1011 | 0.61••+++ (0.61–1.05) | 2.7∗ (2.45–2.83) | ||
Results are expressed as median (lower quartile–upper quartile). •,••,•••Significance between control cells and cells incubated with NPs of a given size and concentration (•P < 0.05, ••P < 0.01, •••P < 0.001). ∗Significance over time (between 24 h and 72 h) in cells incubated with NPs of a given size and concentration (∗P < 0.05). +++: Significance between cells incubated with 20 nm NPs at concentrations of 1.6 × 109 pcs/mL and 1.6 × 1011 pcs/mL (+++P < 0.001).