Table 18.
Catalase activity of A549 cells after 24 h and 72 h incubation with 20 nm and 100 nm Au NPs (pcs/mL).
| Control or pcs/mL | 24 h∗ Catalase activity (U/mg proteins) |
72 h Catalase activity (U/mg proteins) |
||
|---|---|---|---|---|
| Control• | 2.07 (1.94-2.2) | 0.74 (0.67-0.8) | ||
| 20 nm | 100 nm | 20 nm | 100 nm | |
| 1.6 × 107 | 1.94 (1.56-2.13) | 3.46¥ (3.27-3.65) | ||
| 1.6 × 109 + ¥ | 1.18 (0.8-1.43) | 3.02 (2.96-3.53) | 1.751 (1.37-2.96) | 8.09•••∗∗ (7.46-8.45) |
| 1.6 × 1011 | 5.18+++ (4.99-5.3) | 6.89•••++ (6.38-7.21) | ||
Results are expressed as median (lower quartile–upper quartile). •••Significance between control cells and cells incubated with NPs of a given size and concentration (•••P < 0.001). ∗∗Significance over time (between 24 h and 72 h) in cells incubated with NPs of a given size and concentration (∗∗P < 0.01). ++, +++: Significance between cells incubated with 20 nm NPs at concentrations of 1.6 × 109 pcs/mL and 1.6 × 1011 pcs/mL (++P < 0.01, +++P < 0.001). ¥: significance between cells incubated with 100 nm NPs at concentrations of 1.6 × 109 pcs/mL and 1.6 × 107 pcs/mL (¥P < 0.01).