Table 2.
Concentration of 8-isoprostane in HEK 293 T cells after 24 h and 72 h incubation with 20 nm and 100 nm Au NPs (pcs/mL).
| Control or pcs/mL | 24 h∗ 8-isoprostane (pg/mL) |
72 h 8-isoprostane (pg/mL) |
||
|---|---|---|---|---|
| Control • | 237.7 (232.4–246.4) | 272.3∗ (265.7–287. 1) | ||
| 20 nm | 100 nm | 20 nm | 100 nm | |
| 1.6 × 107 | 235.9 (234.1–242.4) | 250.5∗ (249.5–250.5) | ||
| 1.6 × 109 | 235.0 (225.8–244.3) | 241.4 (232.4–245.3) | 248.41 (242.4–259.5) | 268.3∗ (256–282.4) |
| 1.6 × 1011 | 237.7 (230.7–246.4) | 229.9••• (226.6–238.6) | ||
Results are expressed as median (lower quartile–upper quartile). •••Significance between control cells and cells incubated with NPs of a given size and concentration (P < 0.001). ∗Significance over time (between 24h and 72h) in cells incubated with NPs of a given size and concentration (P < 0.05).