Table 3.
Concentration of protein carbonyls in HEK 293 T cells after 24 h and 72 h incubation with 20 nm and 100 nm Au NPs (pcs/mL).
| Control or pcs/mL | 24 h∗ Protein carbonyls (nmol/mg proteins) |
72 h Protein carbonyls (nmol/mg proteins) |
||
|---|---|---|---|---|
| Control • | 1059 (1052.5–1065.8) | 1540.9∗∗ (1531–1545.9) | ||
| 20 nm | 100 nm | 20 nm | 100 nm | |
| 1.6×107 | 859.9 (851.8–863.9) | 1161.1 (1149.2–1176.1) | ||
| 1.6×109 + | 1098.8 (1090.7–1104.5) | 762.2• (759.1–765.9) | 1322.8 (1307.8–1342.3) | 924.2•• (918.5–937.0) |
| 1.6×1011 | 769.5+ (768.8–776.7) | 1254.0 (1248.0–1263.0) | ||
Results are expressed as median (lower quartile–upper quartile). •, ••Significance between control cells and cells incubated with NPs of a given size and concentration (•P < 0.05, ••P < 0.01). ∗∗Significance over time (between 24 h and 72 h) in cells incubated without/with NPs of a given size and concentration (P < 0.01). +: Significance between cells incubated with 20 nm NPs at the concentration of 1.6 × 109 pcs/mL and cells incubated with 20 nm NPs of different concentration (P < 0.05).