Table 7.
TEAC of A375 cells after 24 h and 72 h incubation with 20 nm and 100 nm Au NPs (pcs/mL).
| Control or pcs/mL | 24 h∗ TEAC (mmol of trolox/μg proteins) |
72 h TEAC (mmol of trolox/μg proteins) |
||
|---|---|---|---|---|
| Control • | 0.049 (0.049–0.049) | 0.058 (0.058–0.060) | ||
| 20 nm | 100 nm | 20 nm | 100 nm | |
| 1.6×107 | 0.053 (0.052–0.053) | 0.045•¥¥¥ (0.043–0.047) | ||
| 1.6×109 ¥ | 0.042 (0.041–0.043) | 0.051 (0.044–0.053) | 0.057∗∗ (0.050–0.060) | 0.066∗ (0.060–0.069) |
| 1.6×1011 | 0.050 (0.048–0.065) | 0.050 (0.049–0.055) | ||
Results are expressed as median (lower quartile–upper quartile). •Significance between control cells and cells incubated with NPs of a given size and concentration (•P < 0.05). ∗, ∗∗Significance over time (between 24 h and 72 h) in cells incubated with NPs of a given size and concentration (∗P < 0.05, ∗∗P < 0.01). ¥¥¥: Significance between cells incubated with 100 nm NPs with the concentration of 1.6 × 109 pcs/mL and cells incubated with 100 nm NPs of a given concentration (P < 0.001).