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. 2022 Jul 22;13:925985. doi: 10.3389/fimmu.2022.925985

Table 1.

Ongoing and currently recruiting clinical trials involving CAR T-cell therapies for solid tumors (22).

Intervention Condition Location ClinicalTrials.gov Identifier
CEA CAR T-cells Pancreatic Cancer Chongqing University Cancer Hospital
Chongqing, Chongqing, China
NCT04348643
CD276 CAR T-cells Advanced Pancreatic Cancer Li Yu
Shenzhen, Guangdong, China
NCT05143151
CT041 autologous CAR T-cell Pancreatic Cancer Anhui Provincial Cancer Hospital
Hefei, Anhui, China
NCT04581473
BPX-601 CAR T-cells Metastatic Castration-resistant Prostate Cancer, Metastatic Prostate Cancer,
Metastatic Pancreatic Ductal Adenocarcinoma,
Metastatic Pancreatic Cancer and
Metastatic Pancreatic Adenocarcinoma
Moffitt Cancer Center
Tampa, FL, USA
NCT02744287
Anti-hCD70 CAR transduced PBL Pancreatic Cancer National Institutes of Health Clinical Center
Bethesda, MD, USA
NCT02830724
CEA CAR T-cells Breast Cancer Chongqing University Cancer Hospital
Chongqing, Chongqing, China
NCT04348643
4S CAR T-cells Breast Cancer The Seventh Affiliated Hospital, Sun Yat-Sen University
Shenzhen, Guangdong, China
NCT04430595
CD44v6-specific CAR T-cells Cancers Which Are CD44v6 Positive Shenzhen Children’s Hospital, Shenzhen, Guangdong, China NCT04427449
Anti-hCD70 CAR transduced PBL Breast Cancer National Institutes of Health Clinical Center, Bethesda, MD, USA NCT02830724
AIC100 CAR T-cells Anaplastic Thyroid Cancer and
Relapsed/Refractory Poorly Differentiated Thyroid Cancer
Weill Cornell Medical College
New York, NY, USA
NCT04420754
single dose of CAR T-GFRa4 cells Metastatic Medullary Thyroid Cancer University of Pennsylvania
Philadelphia, PA, USA
NCT04877613
EGFRv III -CAR transduced PBL Malignant Glioma National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, MD, USA NCT01454596
anti-CD133-CAR vector-transduced T cells Brain Tumor Biotherapeutic, Department and Pediatrics Department of Chinese PLA General Hospital Beijing, Beijing, China NCT02541370