Skip to main content
. 2022 Jul 22;13:925985. doi: 10.3389/fimmu.2022.925985

Table 2.

Ongoing and currently recruiting phase III clinical trials involving CAR T-cell therapies for hematologic malignancies (22).

Intervention Condition Location ClinicalTrials.gov Identifier
Anti-CD19 CAR T-cells with concurrent BTK inhibitor for BCL BCL Union Hospital, Wuhan, Hubei, China NCT05020392
CAR-transduced autologous T cell intravenous infusion in subjects with R/R DLBCL with chemotherapy R/R DLBCL Multi-center study NCT03391466
Anti-CD19 CAR T-cells with chemotherapy or blinatumomab in adults with B-ALL B-ALL Multi-center study NCT04530565
BiRd regimen combined with BCMA CAR T-cell therapy in patients with MM MM The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
NCT04287660
VRd regimen combined with autologous BCMA CAR T-cell therapy in patients with MM MM Multi-center study NCT04923893
Autologous CAR T cell therapy targeting BCMA MM Multi-center study NCT04181827
Efficacy and Safety Study of bb2121 Versus Standard Triplet Regimens in Subjects with R/R Multiple Myeloma (RRMM) MM Siteman Cancer Center, Saint Louis, MO, USA
Hackensack University Medical Center, NJ, USA
Sarah Cannon Research Institute Center for Blood, TN, USA
NCT03651128
Intravenous autologous CD19 CAR T-Cells for R/R B-ALL R/R B-ALL UKM Medical Centre
Bandar Tun Razak, Kuala Lumpur, Malaysia
NCT03937544
Tisagenlecleucel in adult patients with aggressive B-cell NHL B-cell NHL University of Chicago Medical Center, Hematology & Oncology, IL, USA
Sarah Cannon, Research Institute, TN, USA
NCT03570892