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(A) Kaplan-Meier analysis of progression-free survival comparing CDK4/6i combinations with visceral vs. non-visceral disease. (B) Kaplan-Meier analysis of progression-free survival comparing CDK 4/6i combinations with de novo and recurrent metastatic presentation. Top panel: pooled analysis; middle panel: for aromatase inhibitor combinations; Bottom panel for fulvestrant combinations.
