Skip to main content
. 2022 Aug 5;13:4567. doi: 10.1038/s41467-022-32349-2

Fig. 5. Images of the targeting probes in vivo.

Fig. 5

a–c Fluorescence images of whole mice, main organs, and tumours at different times after injection of different probes into the tail vein of mice with 4T1 tumours in situ. Metabolic analysis of the probes in mouse organs and blood. Colour scale: greyscale images were converted to pseudocolour images, and blue to red represents the fluorescence intensity values of BDP from low to high, FL Fluorescence. Data are presented as the means ± s.d. (n = 5 mice per group). d, e 2D deep-hypothermia fluorescence imaging of NADH and FAD, the redox ratio of NADH/(NADH + FAD), and the corresponding area histogram of 4T1 tumours at different times after injection of PCoA@M into mice. Colour scale: blue to red represents relative fluorescence intensity values of NADH and FAD from low to high. f HE staining of brain tissue from 4T1 tumour-bearing mice after different treatments.