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. 2022 Apr 8;116(8):745–749. doi: 10.1093/trstmh/trac019

Table 1.

Characteristics and outcomes of eight cases of asymptomatic L. loa microfilaraemia in a malaria vaccine trial in Equatorial Guinea.

Patient number Gender Age (years) Number of smears before microfilariae detected Microfilariae/mL at time of initial detection qPCR at time of initial microscopic detection Eosinophil count at time of initial detection (×103/mm3) Treatment Eosinophil count post-treatment (×103/mm3) Outcome
1 M 21 2 2500 Positive 0.81 DEC ×2 Cleared microfilariae
2 M 61 3 3000 Positive 1.93 DEC 0.46 Cleared microfilariae
3 M 30 5 3000 Positive 1.21 DEC 0.42 Cleared microfilariae
4 M 25 1 15000 ND 0.83 DEC Cleared microfilariae
5 M 23 2 1500 ND 1.36 None Lost to follow-up
6 M 21 14 1500 ND 1.15 None (DEC not taken) Cleared microfilariae without treatment
7 F 50 3 6000 Negative 0.48 DEC ×2 0.16 Cleared microfilariae, then recurred and was re-treated
8 M 24 6 500 ND 1.1 DEC 0.64 Cleared microfilariae, continued in trial

ND: not done.

Eosinophilia was defined as an eosinophil count >0.5×103/mm3 in peripheral blood.