Table 1.
Patient number | Gender | Age (years) | Number of smears before microfilariae detected | Microfilariae/mL at time of initial detection | qPCR at time of initial microscopic detection | Eosinophil count at time of initial detection (×103/mm3) | Treatment | Eosinophil count post-treatment (×103/mm3) | Outcome |
---|---|---|---|---|---|---|---|---|---|
1 | M | 21 | 2 | 2500 | Positive | 0.81 | DEC ×2 | – | Cleared microfilariae |
2 | M | 61 | 3 | 3000 | Positive | 1.93 | DEC | 0.46 | Cleared microfilariae |
3 | M | 30 | 5 | 3000 | Positive | 1.21 | DEC | 0.42 | Cleared microfilariae |
4 | M | 25 | 1 | 15000 | ND | 0.83 | DEC | – | Cleared microfilariae |
5 | M | 23 | 2 | 1500 | ND | 1.36 | None | – | Lost to follow-up |
6 | M | 21 | 14 | 1500 | ND | 1.15 | None (DEC not taken) | – | Cleared microfilariae without treatment |
7 | F | 50 | 3 | 6000 | Negative | 0.48 | DEC ×2 | 0.16 | Cleared microfilariae, then recurred and was re-treated |
8 | M | 24 | 6 | 500 | ND | 1.1 | DEC | 0.64 | Cleared microfilariae, continued in trial |
ND: not done.
Eosinophilia was defined as an eosinophil count >0.5×103/mm3 in peripheral blood.