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. 2022 Jul 25;54(7):1024–1037. doi: 10.1038/s12276-022-00806-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a, b Expression of PTEN protein was analyzed by western blot assay. ^****p < 0.0001. c, d PTEN protein expression after different circROCK1-E3/E4 and miR-532-5p interventions was measured by western blot. ^****p < 0.0001. e, f Cell proliferation ability changes were checked by a CCK8 assay and an EdU assay. ^****p < 0.0001. g, h Cell motility changes were evaluated by a transwell assay. ^****p < 0.0001. All data are presented as the mean ± SD from three independent experiments.