. 2022 Jul 25;54(7):1024–1037. doi: 10.1038/s12276-022-00806-z

Table 2.

Association of circROCK1-E3/E4 expression with clinicopathological features of osteosarcoma.

Features	No. of cases	circROCK1-E3/E4		p-value
Features	No. of cases	High	Low	p-value
Age at diagnosis				1.000^a
<18	37	18	19
≥18	13	7	6
Gender				1.000^a
Female	29	14	15
Male	21	11	10
Histological subtype				1.000^a
Osteoblastic	17	8	9
Chondroblastic	10	5	5
Fibroblastic	14	8	6
Mixed	9	4	5
Clinical stage				0.007^b
I + IIA	18	14	4
IIB/III	32	11	21
Distant metastasis				0.023^b
Absent	9	8	1
Present	41	17	24
Tumor size (cm)				0.038^a
<5	18	13	5
≥5	32	12	20
Anatomic location				1.000^a
Tibia/femur	37	19	18
Elsewhere	13	6	7

^ap-value obtained from Pearson Chi-Square test.

^bp-value obtained from Fisher’s Exact Test.