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. 2022 Feb 6;21(5):818–834. doi: 10.1002/pst.2195

TABLE 3.

Parameter estimates of the ADC‐027 trial using different borrowing methods

Method Time effect β5 Treatment effect β6
Posterior mean Posterior SD 95% CI Posterior mean Posterior SD 95% CI
No borrowing 0.521 0.039 (0.444, 0.596) −0.022 0.051 (0.121, 0.079)
Conditional MPP 0.462 0.026 (0.411, 0.514) 0.034 0.040 (0.045, 0.112)
Marginal MPP 0.477 0.032 (0.416, 0.542) 0.022 0.046 (0.068, 0.109)
Commensurate prior 0.516 0.039 (0.441, 0.592) −0.015 0.050 (0.117, 0.081)
Pooling 0.459 0.025 (0.411, 0.508) 0.039 0.040 (0.039, 0.116)