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Volcano plots of proteomic signatures. (A): marked differences between DS cells (DSC) and healthy control cells (CC); (B): lack of effect of AOAA in healthy control cells; (C): prominent effect of AOAA in DS cells. "Not Sig" indicates differences that are below the significance level of p<0.05 (black dots). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
