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. 2022 Jul 22;13:921728. doi: 10.3389/fimmu.2022.921728

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Copyright © 2022 Yap, Ueda, Kanemitsu, Takeda, Fukumitsu, Fukuda, Uemura, Tajiri, Ohkubo, Maeno, Ito, Oguri, Ugawa and Niimi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expressions after PolyIC–WD–TNF in HF19 cells. HF19 cells were initially treated with Poly (I:C) for 24 h and were then washed and rested for 24 h before secondarily treated with TNFα for another 24 h. Preexposure of HF19 cells to Poly (I:C) significantly increased TNFα-induced IL6 expressions (P < 0.05) but not IL1B, IL8, and MMP8. N = 3. Values with * were defined significant when compared to (-)-WD-(-) while *above bar were significant between two variables; n.s means not significant.